From Wikipedia, the free encyclopedia
Protein-coding gene in the species Homo sapiens
Sodium channel subunit beta-2 is a
protein that in humans is encoded by the SCN2B
gene .
[5]
[6]
See also
References
Further reading
Hartshorne RP, Catterall WA (1984).
"The sodium channel from rat brain. Purification and subunit composition" . J. Biol. Chem . 259 (3): 1667–75.
doi :
10.1016/S0021-9258(17)43460-0 .
PMID
6319405 .
Adams MD, Kerlavage AR, Fleischmann RD, et al. (1995).
"Initial assessment of human gene diversity and expression patterns based upon 83 million nucleotides of cDNA sequence" (PDF) . Nature . 377 (6547 Suppl): 3–174.
PMID
7566098 .
Isom LL, Ragsdale DS, De Jongh KS, et al. (1996).
"Structure and function of the beta 2 subunit of brain sodium channels, a transmembrane glycoprotein with a CAM motif" . Cell . 83 (3): 433–42.
doi :
10.1016/0092-8674(95)90121-3 .
PMID
8521473 .
S2CID
13998841 .
Eubanks J, Srinivasan J, Dinulos MB, et al. (1997). "Structure and chromosomal localization of the beta2 subunit of the human brain sodium channel". NeuroReport . 8 (12): 2775–9.
doi :
10.1097/00001756-199708180-00025 .
PMID
9295116 .
S2CID
21051920 .
Bolino A, Seri M, Caroli F, et al. (1999).
"Exclusion of the SCN2B gene as candidate for CMT4B" . Eur. J. Hum. Genet . 6 (6): 629–34.
doi :
10.1038/sj.ejhg.5200220 .
PMID
9887383 .
Strausberg RL, Feingold EA, Grouse LH, et al. (2003).
"Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences" . Proc. Natl. Acad. Sci. U.S.A . 99 (26): 16899–903.
Bibcode :
2002PNAS...9916899M .
doi :
10.1073/pnas.242603899 .
PMC
139241 .
PMID
12477932 .
Clark HF, Gurney AL, Abaya E, et al. (2003).
"The Secreted Protein Discovery Initiative (SPDI), a Large-Scale Effort to Identify Novel Human Secreted and Transmembrane Proteins: A Bioinformatics Assessment" . Genome Res . 13 (10): 2265–70.
doi :
10.1101/gr.1293003 .
PMC
403697 .
PMID
12975309 .
Ota T, Suzuki Y, Nishikawa T, et al. (2004).
"Complete sequencing and characterization of 21,243 full-length human cDNAs" . Nat. Genet . 36 (1): 40–5.
doi :
10.1038/ng1285 .
PMID
14702039 .
Gerhard DS, Wagner L, Feingold EA, et al. (2004).
"The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)" . Genome Res . 14 (10B): 2121–7.
doi :
10.1101/gr.2596504 .
PMC
528928 .
PMID
15489334 .
Kim DY, Ingano LA, Carey BW, et al. (2005).
"Presenilin/gamma-secretase-mediated cleavage of the voltage-gated sodium channel beta2-subunit regulates cell adhesion and migration" . J. Biol. Chem . 280 (24): 23251–61.
doi :
10.1074/jbc.M412938200 .
PMID
15833746 .
External links
This article incorporates text from the
United States National Library of Medicine , which is in the
public domain .