Gap junction beta-5 protein (GJB5), also known as connexin-31.1 (Cx31.1), is a
protein that in humans is encoded by the GJB5gene.[5]
Function
Gap junctions are conduits that allow the direct cell-to-cell passage of small cytoplasmic molecules, including ions, metabolic intermediates, and second messengers, and thereby mediate intercellular metabolic and electrical communication. Gap junction channels consist of
connexin protein subunits, which are encoded by a multigene family.[5]
Richard G, Smith LE, Bailey RA, et al. (1998). "Mutations in the human connexin gene GJB3 cause erythrokeratodermia variabilis". Nat. Genet. 20 (4): 366–9.
doi:
10.1038/3840.
PMID9843209.
S2CID841727.