From Wikipedia, the free encyclopedia
Protein-coding gene in the species Homo sapiens
Potassium channel, subfamily K, member 13 , also known as KCNK13 is a human
gene . The
protein encoded by this gene, K2P 13.1 is a
potassium channel containing two pore-forming P domains.
[5]
[6]
See also
References
^
a
b
c
GRCh38: Ensembl release 89: ENSG00000152315 –
Ensembl , May 2017
^
a
b
c
GRCm38: Ensembl release 89: ENSMUSG00000045404 –
Ensembl , May 2017
^
"Human PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .
^
"Mouse PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .
^ Rajan S, Wischmeyer E, Karschin C, Preisig-Müller R, Grzeschik KH, Daut J, Karschin A, Derst C (March 2001).
"THIK-1 and THIK-2, a novel subfamily of tandem pore domain K+ channels" . J. Biol. Chem . 276 (10): 7302–11.
doi :
10.1074/jbc.M008985200 .
PMID
11060316 .
^ Goldstein SA, Bayliss DA, Kim D, Lesage F, Plant LD, Rajan S (December 2005).
"International Union of Pharmacology. LV. Nomenclature and molecular relationships of two-P potassium channels" . Pharmacol. Rev . 57 (4): 527–40.
doi :
10.1124/pr.57.4.12 .
PMID
16382106 .
S2CID
7356601 .
Further reading
Strausberg RL, Feingold EA, Grouse LH, Derge JG, Klausner RD, Collins FS, Wagner L, Shenmen CM, Schuler GD (2002).
"Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences" . Proc. Natl. Acad. Sci. U.S.A . 99 (26): 16899–903.
Bibcode :
2002PNAS...9916899M .
doi :
10.1073/pnas.242603899 .
PMC
139241 .
PMID
12477932 .
Fearon IM, Campanucci VA, Brown ST, Hudasek K, o'Kelly IM, Nurse CA (2006).
"Acute Hypoxic Regulation of Recombinant THIK-1 Stably Expressed in HEK293 Cells" . The Arterial Chemoreceptors . ADVANCES IN EXPERIMENTAL MEDICINE AND BIOLOGY. Vol. 580. pp.
203–8, discussion 351–9 .
doi :
10.1007/0-387-31311-7_31 .
ISBN
978-0-387-31310-8 .
PMID
16683720 .
Goldstein SA, Bockenhauer D, O'Kelly I, Zilberberg N (2001).
"Potassium leak channels and the KCNK family of two-P-domain subunits" . Nat. Rev. Neurosci . 2 (3): 175–84.
doi :
10.1038/35058574 .
PMID
11256078 .
S2CID
9682396 .
Gerhard DS, Wagner L, Feingold EA, Shenmen CM, Grouse LH, Schuler G, Klein SL, Old S, Rasooly R (2004).
"The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)" . Genome Res . 14 (10B): 2121–7.
doi :
10.1101/gr.2596504 .
PMC
528928 .
PMID
15489334 .
Theilig F, Goranova I, Hirsch JR, Wieske M, ÜNsal S, Bachmann S, Veh RW, Derst C (2008).
"Cellular localization of THIK-1 (K(2P)13.1) and THIK-2 (K(2P)12.1) K channels in the mammalian kidney" . Cell. Physiol. Biochem . 21 (1–3): 63–74.
doi :
10.1159/000113748 .
PMID
18209473 .
Gierten J, Ficker E, Bloehs R, Schlömer K, Kathöfer S, Scholz E, Zitron E, Kiesecker C, Bauer A (2008).
"Regulation of two-pore-domain (K2P) potassium leak channels by the tyrosine kinase inhibitor genistein" . Br. J. Pharmacol . 154 (8): 1680–90.
doi :
10.1038/bjp.2008.213 .
PMC
2518462 .
PMID
18516069 .
External links