From Wikipedia, the free encyclopedia
Protein-coding gene in the species Homo sapiens
Chloride channel CLIC-like 1 also known as CLCC1 is a human
gene .
[5]
[6]
The
protein encoded by this gene is a
chloride channel which is related in sequence to the
S. cerevisiae MID-1 stretch-activated channel. CLCC1 is located in the membranes of intracellular compartments including
endoplasmic reticulum and the
Golgi apparatus . It is highly expressed in the testis and moderately in the spleen, liver, kidney, heart, brain, and lung.
[6]
References
^
a
b
c
GRCh38: Ensembl release 89: ENSG00000121940 –
Ensembl , May 2017
^
a
b
c
GRCm38: Ensembl release 89: ENSMUSG00000027884 –
Ensembl , May 2017
^
"Human PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .
^
"Mouse PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .
^ Nagase T, Ishikawa K, Suyama M, Kikuno R, Miyajima N, Tanaka A, Kotani H, Nomura N, Ohara O (October 1998).
"Prediction of the coding sequences of unidentified human genes. XI. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro" . DNA Res . 5 (5): 277–86.
doi :
10.1093/dnares/5.5.277 .
PMID
9872452 .
^
a
b Nagasawa M, Kanzaki M, Iino Y, Morishita Y, Kojima I (June 2001).
"Identification of a novel chloride channel expressed in the endoplasmic reticulum, golgi apparatus, and nucleus" . J. Biol. Chem . 276 (23): 20413–8.
doi :
10.1074/jbc.M100366200 .
PMID
11279057 .
Further reading
Nagase T, Ishikawa K, Suyama M, et al. (1998).
"Prediction of the coding sequences of unidentified human genes. XI. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro" . DNA Res . 5 (5): 277–86.
doi :
10.1093/dnares/5.5.277 .
PMID
9872452 .
Strausberg RL, Feingold EA, Grouse LH, et al. (2002).
"Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences" . Proc. Natl. Acad. Sci. U.S.A . 99 (26): 16899–903.
Bibcode :
2002PNAS...9916899M .
doi :
10.1073/pnas.242603899 .
PMC
139241 .
PMID
12477932 .
Kimura K, Wakamatsu A, Suzuki Y, et al. (2006).
"Diversification of transcriptional modulation: Large-scale identification and characterization of putative alternative promoters of human genes" . Genome Res . 16 (1): 55–65.
doi :
10.1101/gr.4039406 .
PMC
1356129 .
PMID
16344560 .
Suzuki Y, Yamashita R, Shirota M, et al. (2004).
"Sequence Comparison of Human and Mouse Genes Reveals a Homologous Block Structure in the Promoter Regions" . Genome Res . 14 (9): 1711–8.
doi :
10.1101/gr.2435604 .
PMC
515316 .
PMID
15342556 .
Nagasawa M, Kanzaki M, Iino Y, et al. (2001).
"Identification of a novel chloride channel expressed in the endoplasmic reticulum, golgi apparatus, and nucleus" . J. Biol. Chem . 276 (23): 20413–8.
doi :
10.1074/jbc.M100366200 .
PMID
11279057 .
Ota T, Suzuki Y, Nishikawa T, et al. (2004).
"Complete sequencing and characterization of 21,243 full-length human cDNAs" . Nat. Genet . 36 (1): 40–5.
doi :
10.1038/ng1285 .
PMID
14702039 .
External links