From Wikipedia, the free encyclopedia
Chemical compound
RU-2309
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Other names | 18-Methylmetribolone; 17α-Methyltetrahydrogestrinone; 17α-Methyl-THG; ∆9,11-17α,18-dimethyl-19-nortestosterone; 17α,18-Dimethylestr-4,9,11-trien-17β-ol-3-one |
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Drug class |
Androgen;
Anabolic steroid |
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(8S,13S,14S,17S)-13-ethyl-17-hydroxy-17-methyl-1,2,6,7,8,14,15,16-octahydrocyclopenta[a]phenanthren-3-one
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PubChem
CID | |
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ChemSpider | |
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Formula | C20H26O2 |
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Molar mass | 298.426 g·mol−1 |
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3D model (
JSmol) | |
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CC[C@]12C=CC3=C4CCC(=O)C=C4CC[C@H]3[C@@H]1CC[C@]2(C)O
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InChI=1S/C20H26O2/c1-3-20-11-8-16-15-7-5-14(21)12-13(15)4-6-17(16)18(20)9-10-19(20,2)22/h8,11-12,17-18,22H,3-7,9-10H2,1-2H3/t17-,18+,19+,20+/m1/s1 Key:KTIKZXSPPAGDBN-FYQPLNBISA-N
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RU-2309, also known as 18-methylmetribolone, δ9,11-17α,18-dimethyl-19-nortestosterone, or 17α,18-dimethylestr-4,9,11-trien-17β-ol-3-one, is a
17α-alkylated
androgen/
anabolic steroid (AAS) of the
19-nortestosterone group which was never marketed.
[1]
[2]
[3] It is the C18
methyl or C13β
ethyl
derivative of
metribolone.
[1]
[2] The compound is closely related to
tetrahydrogestrinone (THG), which has the same
chemical structure as RU-2309 except for possessing an
ethyl group at the C17α position instead of a
methyl group.
[4] Hence, it could also be referred to as 17α-methyl-THG.
[4] RU-2309 shows high
affinity for the
androgen,
progesterone, and
glucocorticoid receptors.
[1]
[2]
[3]
See also
References
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ARTooltip Androgen receptor | Agonists | |
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SARMsTooltip Selective androgen receptor modulator | |
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Antagonists | |
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GPRC6A | |
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GRTooltip Glucocorticoid receptor | |
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PRTooltip Progesterone receptor | Agonists |
- Testosterone derivatives: Progestins:
6,6-Difluoronorethisterone
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6,6-Difluoronorethisterone acetate
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17α-Allyl-19-nortestosterone
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Allylestrenol
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Altrenogest
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Chloroethynylnorgestrel
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Cingestol
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Danazol
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Desogestrel
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Dienogest
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Ethinylandrostenediol
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Ethisterone
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Ethynerone
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Etonogestrel
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Etynodiol
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Etynodiol diacetate
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Gestodene
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Gestrinone
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Levonorgestrel
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Levonorgestrel esters (e.g.,
levonorgestrel butanoate)
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Lynestrenol
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Lynestrenol phenylpropionate
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Metynodiol
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Metynodiol diacetate
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Norelgestromin
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Norethisterone (norethindrone)
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Norethisterone esters (e.g.,
norethisterone acetate,
norethisterone enanthate)
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Noretynodrel
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Norgesterone
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Norgestimate
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Norgestrel
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Norgestrienone
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Norvinisterone
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Oxendolone
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Quingestanol
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Quingestanol acetate
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Tibolone
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Tigestol
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Tosagestin; Anabolic–androgenic steroids:
11β-Methyl-19-nortestosterone
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11β-Methyl-19-nortestosterone dodecylcarbonate
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19-Nor-5-androstenediol
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19-Nor-5-androstenedione
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19-Nordehydroepiandrosterone
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Bolandiol
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Bolandiol dipropionate
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Bolandione
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Dimethisterone
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Dienedione
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Dienolone
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Dimethandrolone
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Dimethandrolone buciclate
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Dimethandrolone dodecylcarbonate
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Dimethandrolone undecanoate
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Dimethyldienolone
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Dimethyltrienolone
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Ethyldienolone
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Ethylestrenol (ethylnandrol)
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Methyldienolone
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Metribolone (R-1881)
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Methoxydienone (methoxygonadiene)
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Mibolerone
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Nandrolone
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Nandrolone esters (e.g.,
nandrolone decanoate,
nandrolone phenylpropionate)
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Norethandrolone
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Normethandrone (methylestrenolone, normethandrolone, normethisterone)
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RU-2309
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Tetrahydrogestrinone
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Trenbolone (trienolone)
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Trenbolone esters (e.g.,
trenbolone acetate,
trenbolone enanthate)
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Trendione
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Trestolone
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Trestolone acetate
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Mixed (
SPRMsTooltip Selective progesterone receptor modulators) | |
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Antagonists | |
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mPRTooltip Membrane progesterone receptor (
PAQRTooltip Progestin and adipoQ receptor) | |
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