From Wikipedia, the free encyclopedia
Protein-coding gene in the species Homo sapiens
Sodium-dependent phosphate transporter 1 is a
protein that in humans is encoded by the SLC20A1
gene .
[5]
[6]
Retrovirus receptors allow infection of human and murine cells by various
retroviruses . The receptors that have been identified at the molecular level include
CD4 (MIM 186940) for
human immunodeficiency virus , Rec1 for murine ecotropic virus, and GLVR1 for
gibbon ape leukemia virus (see MIM 182090). These 3 proteins show no homology to one another at the DNA or protein level. GLVR1 is a
sodium-dependent phosphate symporter .[supplied by OMIM]
[6]
Research
It was reported that mutations of the gene may cause
epispadias or
bladder exstrophy .
[7]
See also
References
^
a
b
c
GRCh38: Ensembl release 89: ENSG00000144136 –
Ensembl , May 2017
^
a
b
c
GRCm38: Ensembl release 89: ENSMUSG00000027397 –
Ensembl , May 2017
^
"Human PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .
^
"Mouse PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .
^ Kavanaugh MP, Miller DG, Zhang W, Law W, Kozak SL, Kabat D, Miller AD (Aug 1994).
"Cell-surface receptors for gibbon ape leukemia virus and amphotropic murine retrovirus are inducible sodium-dependent phosphate symporters" . Proc Natl Acad Sci U S A . 91 (15): 7071–5.
Bibcode :
1994PNAS...91.7071K .
doi :
10.1073/pnas.91.15.7071 .
PMC
44340 .
PMID
8041748 .
^
a
b
"Entrez Gene: SLC20A1 solute carrier family 20 (phosphate transporter), member 1" .
^ Rieke JM, Zhang R, Braun D, Yilmaz Ö, Japp AS, Lopes FM, et al. (2020).
"SLC20A1 Is Involved in Urinary Tract and Urorectal Development" . Frontiers in Cell and Developmental Biology . 8 : 567.
doi :
10.3389/fcell.2020.00567 .
PMC
7426641 .
PMID
32850778 .
Further reading
Takeuchi Y, Vile RG, Simpson G, et al. (1992).
"Feline leukemia virus subgroup B uses the same cell surface receptor as gibbon ape leukemia virus" . J. Virol . 66 (2): 1219–22.
doi :
10.1128/JVI.66.2.1219-1222.1992 .
PMC
240831 .
PMID
1309898 .
Johann SV, Gibbons JJ, O'Hara B (1992).
"GLVR1, a receptor for gibbon ape leukemia virus, is homologous to a phosphate permease of Neurospora crassa and is expressed at high levels in the brain and thymus" . J. Virol . 66 (3): 1635–40.
doi :
10.1128/JVI.66.3.1635-1640.1992 .
PMC
240899 .
PMID
1531369 .
Kaelbling M, Eddy R, Shows TB, et al. (1991).
"Localization of the human gene allowing infection by gibbon ape leukemia virus to human chromosome region 2q11-q14 and to the homologous region on mouse chromosome 2" . J. Virol . 65 (4): 1743–7.
doi :
10.1128/JVI.65.4.1743-1747.1991 .
PMC
239979 .
PMID
1672162 .
O'Hara B, Johann SV, Klinger HP, et al. (1991). "Characterization of a human gene conferring sensitivity to infection by gibbon ape leukemia virus". Cell Growth Differ . 1 (3): 119–27.
PMID
2078500 .
Olah Z, Lehel C, Anderson WB, et al. (1994).
"The cellular receptor for gibbon ape leukemia virus is a novel high affinity sodium-dependent phosphate transporter" . J. Biol. Chem . 269 (41): 25426–31.
doi :
10.1016/S0021-9258(18)47267-5 .
PMID
7929240 .
Miller DG, Miller AD (1994).
"A family of retroviruses that utilize related phosphate transporters for cell entry" . J. Virol . 68 (12): 8270–6.
doi :
10.1128/JVI.68.12.8270-8276.1994 .
PMC
237294 .
PMID
7966619 .
Johann SV, van Zeijl M, Cekleniak J, O'Hara B (1993).
"Definition of a domain of GLVR1 which is necessary for infection by gibbon ape leukemia virus and which is highly polymorphic between species" . J. Virol . 67 (11): 6733–6.
doi :
10.1128/JVI.67.11.6733-6736.1993 .
PMC
238113 .
PMID
8411375 .
Tatsumi S, Segawa H, Morita K, et al. (1998).
"Molecular cloning and hormonal regulation of PiT-1, a sodium-dependent phosphate cotransporter from rat parathyroid glands" . Endocrinology . 139 (4): 1692–9.
doi :
10.1210/endo.139.4.5925 .
PMID
9528951 .
Palmer G, Manen D, Bonjour JP, Caverzasio J (1999). "Characterization of the human Glvr-1 phosphate transporter/retrovirus receptor gene and promoter region". Gene . 226 (1): 25–33.
doi :
10.1016/S0378-1119(98)00572-1 .
PMID
9889306 .
Jono S, McKee MD, Murry CE, et al. (2000).
"Phosphate regulation of vascular smooth muscle cell calcification" . Circ. Res . 87 (7): E10–7.
doi :
10.1161/01.RES.87.7.e10 .
PMID
11009570 .
Farrell KB, Russ JL, Murthy RK, Eiden MV (2002).
"Reassessing the role of region A in Pit1-mediated viral entry" . J. Virol . 76 (15): 7683–93.
doi :
10.1128/JVI.76.15.7683-7693.2002 .
PMC
136385 .
PMID
12097582 .
Bottger P, Pedersen L (2003).
"Two highly conserved glutamate residues critical for type III sodium-dependent phosphate transport revealed by uncoupling transport function from retroviral receptor function" . J. Biol. Chem . 277 (45): 42741–7.
doi :
10.1074/jbc.M207096200 .
PMID
12205090 .
Strausberg RL, Feingold EA, Grouse LH, et al. (2003).
"Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences" . Proc. Natl. Acad. Sci. U.S.A . 99 (26): 16899–903.
Bibcode :
2002PNAS...9916899M .
doi :
10.1073/pnas.242603899 .
PMC
139241 .
PMID
12477932 .
Matsuda A, Suzuki Y, Honda G, et al. (2003).
"Large-scale identification and characterization of human genes that activate NF-kappaB and MAPK signaling pathways" . Oncogene . 22 (21): 3307–18.
doi :
10.1038/sj.onc.1206406 .
PMID
12761501 .
Gerhard DS, Wagner L, Feingold EA, et al. (2004).
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)" . Genome Res . 14 (10B): 2121–7.
doi :
10.1101/gr.2596504 .
PMC
528928 .
PMID
15489334 .
Cecil DL, Rose DM, Terkeltaub R, Liu-Bryan R (2005).
"Role of interleukin-8 in PiT-1 expression and CXCR1-mediated inorganic phosphate uptake in chondrocytes" . Arthritis Rheum . 52 (1): 144–54.
doi :
10.1002/art.20748 .
PMID
15641067 .
Hillier LW, Graves TA, Fulton RS, et al. (2005).
"Generation and annotation of the DNA sequences of human chromosomes 2 and 4" . Nature . 434 (7034): 724–31.
Bibcode :
2005Natur.434..724H .
doi :
10.1038/nature03466 .
PMID
15815621 .
Li X, Yang HY, Giachelli CM (2006).
"Role of the sodium-dependent phosphate cotransporter, Pit-1, in vascular smooth muscle cell calcification" . Circ. Res . 98 (7): 905–12.
doi :
10.1161/01.RES.0000216409.20863.e7 .
PMID
16527991 .
Bøttger P, Hede SE, Grunnet M, et al. (2007). "Characterization of transport mechanisms and determinants critical for Na+-dependent Pi symport of the PiT family paralogs human PiT1 and PiT2". Am. J. Physiol., Cell Physiol . 291 (6): C1377–87.
doi :
10.1152/ajpcell.00015.2006 .
PMID
16790504 .
This article incorporates text from the
United States National Library of Medicine , which is in the
public domain .
By group
SLC1–10
(1): (2): (3): (4): (5): (6): (7): (8): (9): (10):
SLC11–20
(11): (12): (13): (14): (15): (16): (17): (18): (19): (20):
SLC21–30
(21): (22): (23): (24): (25): (26): (27): (28): (29): (30):
SLC31–40
(31): (32): (33): (34): (35): (36): (37): (38): (39): (40):
SLC41–48
(41): (42): (43): (44): (45): (46): (47): (48):