From Wikipedia, the free encyclopedia
VUF-8430
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Names
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Preferred IUPAC name
2-[(Aminoiminomethyl)amino]ethyl carbamimidothioic acid ester [
citation needed]
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Identifiers
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Abbreviations
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VUF-8430
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ChEMBL
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ChemSpider
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UNII
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InChI=1S/C4H11N5S/c5-3(6)9-1-2-10-4(7)8/h1-2H2,(H3,7,8)(H4,5,6,9) YKey: GSYGTVNTZHFQQH-UHFFFAOYSA-N Y
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Properties
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C4H11N5S
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Molar mass
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161.23 g·mol−1
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log P
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-1.367
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Except where otherwise noted, data are given for materials in their
standard state (at 25 °C [77 °F], 100 kPa).
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Chemical compound
VUF-8430 is a
histamine agonist
[1] selective for the
H4 subtype.
[2]
References
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H1 | Agonists | |
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Antagonists |
- Others:
Atypical antipsychotics (e.g.,
aripiprazole,
asenapine,
brexpiprazole,
brilaroxazine,
clozapine,
iloperidone,
olanzapine,
paliperidone,
quetiapine,
risperidone,
ziprasidone,
zotepine)
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Phenylpiperazine
antidepressants (e.g.,
hydroxynefazodone,
nefazodone,
trazodone,
triazoledione)
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Tetracyclic antidepressants (e.g.,
amoxapine,
loxapine,
maprotiline,
mianserin,
mirtazapine,
oxaprotiline)
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Tricyclic antidepressants (e.g.,
amitriptyline,
butriptyline,
clomipramine,
desipramine,
dosulepin (dothiepin),
doxepin,
imipramine,
iprindole,
lofepramine,
nortriptyline,
protriptyline,
trimipramine)
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Typical antipsychotics (e.g.,
chlorpromazine,
flupenthixol,
fluphenazine,
loxapine,
perphenazine,
prochlorperazine,
thioridazine,
thiothixene)
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H2 | |
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H3 | |
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H4 | |
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