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Chemical compound
Talastine (trade name Ahanon ) is an
antihistamine .
[1]
Synthesis
The
amide
proton from 4-Benzylphalazone is abstracted with KOH, which is then
alkylated with dimethylaminoethyl
chloride .
[2]
[3]
References
^ Richter G, Kühn E (1990). "[Talastine (Ahanon) as a cause of allergic drug exanthema]". Dermatologische Monatschrift (in German). 176 (2–3): 111–3.
PMID
1973126 .
^
DE 1046625 , Engelbrecht, et al., issued 1958, assigned to VEB Deutsches Hydrierwerk Rodleben
^
US 3017411 , Engelbrecht, et al., issued 1962, assigned to VEB Deutsches Hydrierwerk Rodleben
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