From Wikipedia, the free encyclopedia
Bioinformatician
Chris Sander is a
computational biologist based at the Dana-Farber Cancer Center and Harvard Medical School. Previously he was chair of the Computational Biology Programme at the
Memorial Sloan–Kettering Cancer Center in
New York City .
[7]
[8]
[9]
[10]
[11]
[12]
[13] In 2015, he moved his lab to the
Dana–Farber Cancer Institute
[14] and the Cell Biology Department at
Harvard Medical School .
[15]
Education
Sander originally trained as a physicist, receiving his undergraduate degree from the
University of Berlin in 1967.
[2] After a period studying at the
University of California, Berkeley and the
Niels Bohr Institute in Copenhagen,
[2]
[16] he gained his
PhD degree in theoretical physics from the
State University of New York in 1975. His thesis was titled Analytic properties of bound state wave functions .
[17]
Research
Sander credits his move from theoretical physics to computational biology to
Fred Sanger 's 1977 landmark paper in
Nature ,
[18] in which the nucleotide sequence of
bacteriophage φX174 was published.
[2] Sander has made many contributions to the field of
structural bioinformatics including developing tools such as the
Families of Structurally Similar Proteins (FSSP) database
[19] and the
DSSP algorithm for assigning
secondary structure to the
amino acids of a protein, given the atomic-resolution coordinates of that protein.
[20]
Sander was a founder of the biocomputing program at the
European Molecular Biology Laboratory in Heidelberg, before moving the program to the
European Bioinformatics Institute in Cambridge. He has served as chief information officer for the biopharmaceutical company
Millennium Pharmaceuticals and has been an advisor to
IBM 's Deep Computing Initiative, which produced the
Deep Blue chess computer.
[21]
Awards and honours
Sander is a former Executive Editor for the journal
Bioinformatics . In 2014 he was appointed one of the first Honorary Editors of Bioinformatics .
[22]
Sander was awarded the
ISCB Accomplishment by a Senior Scientist Award in 2010.
[16] He was awarded the 2018
DeLano Award for Computational Biosciences .
[23]
Personal life
Sander is the brother of German actor
Otto Sander .
[24]
References
^ McKay, B. M.; Sansom, C. (2010).
"2010 ISCB Overton Prize Awarded to Steven E. Brenner" . PLOS Computational Biology . 6 (6): e1000831.
Bibcode :
2010PLSCB...6E0831M .
doi :
10.1371/journal.pcbi.1000831 .
PMC
2891695 .
PMID
20585610 .
^
a
b
c
d
"Sander Lab" .
^ Lifson, Shneior;
Sander, Christian (1979). "Antiparallel and parallel β-strands differ in amino acid residue preferences". Nature . 282 (5734): 109–111.
Bibcode :
1979Natur.282..109L .
doi :
10.1038/282109a0 .
PMID
503185 .
S2CID
4284088 .
^ Ouzounis, Christos (1993). The role of sequence conservation in the prediction of protein structure (PhD thesis). University of York.
OCLC
53486615 .
EThOS
uk.bl.ethos.387193 .
^
"At Work: Computational Biology Program Chair Chris Sander | Memorial Sloan-Kettering Cancer Center" . Archived from
the original on 2013-02-21.
^ Holm, L.; Sander, C. (1993). "Protein Structure Comparison by Alignment of Distance Matrices". Journal of Molecular Biology . 233 (1): 123–138.
doi :
10.1006/jmbi.1993.1489 .
PMID
8377180 .
S2CID
9040631 .
^
Chris Sander at
DBLP Bibliography Server
^
Chris Sander publications indexed by
Google Scholar
^
Chris Sander publications indexed by
Microsoft Academic
^
Sander, Chris A.'s publications indexed by the
Scopus bibliographic database. (subscription required)
^ John, B.; Enright, A. J.; Aravin, A.; Tuschl, T.; Sander, C.; Marks, D. S. (2004).
"Human MicroRNA Targets" . PLOS Biology . 2 (11): e363.
doi :
10.1371/journal.pbio.0020363 .
PMC
521178 .
PMID
15502875 .
^ Rost, B.; Sander, C. (1993). "Prediction of Protein Secondary Structure at Better than 70% Accuracy". Journal of Molecular Biology . 232 (2): 584–599.
CiteSeerX
10.1.1.17.1418 .
doi :
10.1006/jmbi.1993.1413 .
PMID
8345525 .
^
Sander, C. ; Schulz, G. E. (1979). "Degeneracy of the information contained in amino acid sequences: Evidence from overlaid genes". Journal of Molecular Evolution . 13 (3): 245–252.
Bibcode :
1979JMolE..13..245S .
doi :
10.1007/BF01739483 .
PMID
228047 .
S2CID
22606882 .
^
"Chris Sander, PhD - DF/HCC" . www.dfhcc.harvard.edu . Retrieved 2019-01-01 .
^
"Chris Sander | Department of CELL BIOLOGY" . cellbio.med.harvard.edu . Retrieved 2019-01-01 .
^
a
b
"2010 Accomplishment by a Senior Scientist Award - Chris Sander" .
^ Sander, C. (1975).
"INIS Collection Search - Single Result" . p. 155. Retrieved 13 August 2015 .
^ Sanger, F.; Air, G. M.; Barrell, B. G.; Brown, N. L.; Coulson, A. R.; Fiddes, J. C.; Hutchison, C. A.; Slocombe, P. M.; Smith, M. (24 February 1977). "Nucleotide sequence of bacteriophage φX174 DNA". Nature . 265 (5596): 687–695.
Bibcode :
1977Natur.265..687S .
doi :
10.1038/265687a0 .
PMID
870828 .
S2CID
4206886 .
^ Holm L, Ouzounis C, Sander C, Tuparev G, Vriend G (1992).
"A database of protein structure families with common folding motifs" . Protein Science . 1 (12): 1691–1698.
doi :
10.1002/pro.5560011217 .
PMC
2142138 .
PMID
1304898 .
^ Kabsch, W.; Sander, C. (1983). "Dictionary of protein secondary structure: Pattern recognition of hydrogen-bonded and geometrical features". Biopolymers . 22 (12): 2577–2637.
doi :
10.1002/bip.360221211 .
PMID
6667333 .
S2CID
29185760 .
^
"Bio-IT World: Horizons - Chris Sander" . Archived from
the original on 23 September 2015. Retrieved 13 August 2015 .
^ "15 years of "Bioinformatics" ". Bioinformatics . 30 (6): 747. 2014.
doi :
10.1093/bioinformatics/btu076 .
PMID
24642573 .
^
"DeLano Award for Computational Biosciences" . www.asbmb.org . Retrieved 15 September 2017 .
^
Biography for Otto Sander at
IMDb . Retrieved 13 August 2015.
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