There are many characterised
protein families with
Glycoside hydrolase activity
EC3.2.1.. These enzymes hydrolyse the glycosidic bond between two or more carbohydrates, or between a carbohydrate and a non-carbohydrate moiety. Families are defined based on their
sequence similarity.[1][2][3] This classification is available on the
CAZy (CArbohydrate-Active EnZymes) web site.[4] Because the fold of proteins is better conserved than their sequences, some of the families can be grouped into 'clans' (
superfamilies). As of October 2011, CAZy includes 128 families of glycosyl hydrolases, grouped into 14 clans.