Beta-galactosidase | |||||||||
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![]() crystal structure of thermus thermophilus a4 beta-galactosidase | |||||||||
Identifiers | |||||||||
Symbol | Glyco_hydro_42 | ||||||||
Pfam | PF02449 | ||||||||
Pfam clan | CL0058 | ||||||||
InterPro | IPR013529 | ||||||||
SCOP2 | 1kwg / SCOPe / SUPFAM | ||||||||
CAZy | GH42 | ||||||||
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Beta-galactosidase trimerisation domain | |||||||||
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![]() crystal structure of thermus thermophilus a4 beta-galactosidase | |||||||||
Identifiers | |||||||||
Symbol | Glyco_hydro_42M | ||||||||
Pfam | PF08532 | ||||||||
Pfam clan | CL0014 | ||||||||
InterPro | IPR013738 | ||||||||
SCOP2 | 1kwg / SCOPe / SUPFAM | ||||||||
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Beta-galactosidase C-terminal domain | |||||||||
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![]() crystal structure of thermus thermophilus a4 beta-galactosidase | |||||||||
Identifiers | |||||||||
Symbol | Glyco_hydro_42C | ||||||||
Pfam | PF08533 | ||||||||
Pfam clan | CL0369 | ||||||||
InterPro | IPR013739 | ||||||||
SCOP2 | 1kwg / SCOPe / SUPFAM | ||||||||
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In molecular biology, glycoside hydrolase family 42 is a family of glycoside hydrolases.
Glycoside hydrolases EC 3.2.1. are a widespread group of enzymes that hydrolyse the glycosidic bond between two or more carbohydrates, or between a carbohydrate and a non-carbohydrate moiety. A classification system for glycoside hydrolases, based on sequence similarity, has led to the definition of >100 different families. [1] [2] [3] This classification is available on the CAZy web site, [4] [5] and also discussed at CAZypedia, an online encyclopedia of carbohydrate active enzymes. [6] [7]
The glycosyl hydrolase 42 family CAZY GH_42 comprises beta-galactosidase enzymes ( EC 3.2.1.23). These enzyme catalyse the hydrolysis of terminal, non-reducing terminal beta-D-galactoside residues. The middle domain of these three-domain enzymes is involved in trimerisation. [8]