From Wikipedia, the free encyclopedia
Protein-coding gene in the species Homo sapiens
RPS20 Available structures
PDB Ortholog search:
PDBe
RCSB List of PDB id codes
4UG0 ,
4V6X ,
5A2Q ,
5AJ0 ,
5FLX ,
4D61 ,
4KZY ,
4KZX ,
4UJC ,
4D5L ,
4UJE ,
4V5Z ,
4KZZ ,
4UJD
Identifiers
Aliases
RPS20 , S20, ribosomal protein S20, uS10External IDs
OMIM :
603682 ;
MGI :
1914677 ;
HomoloGene :
37417 ;
GeneCards :
RPS20 ;
OMA :
RPS20 - orthologs
Wikidata
40S ribosomal protein S20 is a
protein that in
humans is encoded by the RPS20
gene .
[5]
[6]
[7]
Ribosomes , the
organelles that
catalyze
protein synthesis , consist of a
small 40S subunit and a
large 60S subunit . Together these subunits are composed of 4
RNA species and approximately 80 structurally distinct proteins. This gene encodes a
ribosomal protein that is a component of the 40S subunit. The protein belongs to the S10P family of ribosomal proteins. It is located in the
cytoplasm . This gene is co-transcribed with the
small nucleolar RNA gene U54, which is located in its second intron. As is typical for genes encoding ribosomal proteins, there are multiple processed
pseudogenes of this gene dispersed through the genome.
[7]
References
^
a
b
c
GRCh38: Ensembl release 89: ENSG00000008988 –
Ensembl , May 2017
^
a
b
c
GRCm38: Ensembl release 89: ENSMUSG00000028234 –
Ensembl , May 2017
^
"Human PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .
^
"Mouse PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .
^ Kenmochi N, Kawaguchi T, Rozen S, Davis E, Goodman N, Hudson TJ, Tanaka T, Page DC (Aug 1998).
"A map of 75 human ribosomal protein genes" . Genome Res . 8 (5): 509–23.
doi :
10.1101/gr.8.5.509 .
PMID
9582194 .
^ Chu W, Presky DH, Swerlick RA, Burns DK (May 1993).
"Human ribosomal protein S20 cDNA sequence" . Nucleic Acids Res . 21 (7): 1672.
doi :
10.1093/nar/21.7.1672 .
PMC
309385 .
PMID
8479924 .
^
a
b
"Entrez Gene: RPS20 ribosomal protein S20" .
Further reading
Wool IG, Chan YL, Glück A (1996). "Structure and evolution of mammalian ribosomal proteins". Biochem. Cell Biol . 73 (11–12): 933–47.
doi :
10.1139/o95-101 .
PMID
8722009 .
Kato S, Sekine S, Oh SW, et al. (1995). "Construction of a human full-length cDNA bank". Gene . 150 (2): 243–50.
doi :
10.1016/0378-1119(94)90433-2 .
PMID
7821789 .
Kiss-László Z, Henry Y, Bachellerie JP, et al. (1996).
"Site-specific ribose methylation of preribosomal RNA: a novel function for small nucleolar RNAs" . Cell . 85 (7): 1077–88.
doi :
10.1016/S0092-8674(00)81308-2 .
PMID
8674114 .
S2CID
10418885 .
Vladimirov SN, Ivanov AV, Karpova GG, et al. (1996).
"Characterization of the human small-ribosomal-subunit proteins by N-terminal and internal sequencing, and mass spectrometry" . Eur. J. Biochem . 239 (1): 144–9.
doi :
10.1111/j.1432-1033.1996.0144u.x .
PMID
8706699 .
Yoshihama M, Uechi T, Asakawa S, et al. (2002).
"The Human Ribosomal Protein Genes: Sequencing and Comparative Analysis of 73 Genes" . Genome Res . 12 (3): 379–90.
doi :
10.1101/gr.214202 .
PMC
155282 .
PMID
11875025 .
Strausberg RL, Feingold EA, Grouse LH, et al. (2003).
"Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences" . Proc. Natl. Acad. Sci. U.S.A . 99 (26): 16899–903.
Bibcode :
2002PNAS...9916899M .
doi :
10.1073/pnas.242603899 .
PMC
139241 .
PMID
12477932 .
Lehner B, Sanderson CM (2004).
"A Protein Interaction Framework for Human mRNA Degradation" . Genome Res . 14 (7): 1315–23.
doi :
10.1101/gr.2122004 .
PMC
442147 .
PMID
15231747 .
Gerhard DS, Wagner L, Feingold EA, et al. (2004).
"The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)" . Genome Res . 14 (10B): 2121–7.
doi :
10.1101/gr.2596504 .
PMC
528928 .
PMID
15489334 .
Yu Y, Ji H, Doudna JA, Leary JA (2005).
"Mass spectrometric analysis of the human 40S ribosomal subunit: Native and HCV IRES-bound complexes" . Protein Sci . 14 (6): 1438–46.
doi :
10.1110/ps.041293005 .
PMC
2253395 .
PMID
15883184 .
De Bortoli M, Castellino RC, Lu XY, et al. (2006).
"Medulloblastoma outcome is adversely associated with overexpression of EEF1D, RPL30, and RPS20 on the long arm of chromosome 8" . BMC Cancer . 6 : 223.
doi :
10.1186/1471-2407-6-223 .
PMC
1578584 .
PMID
16968546 .
Tu LC, Yan X, Hood L, Lin B (2007).
"Proteomics analysis of the interactome of N-myc downstream regulated gene 1 and its interactions with the androgen response program in prostate cancer cells" . Mol. Cell. Proteomics . 6 (4): 575–88.
doi :
10.1074/mcp.M600249-MCP200 .
PMID
17220478 .
Frum R, Busby SA, Ramamoorthy M, et al. (2007).
"HDM2-binding partners: interaction with translation elongation factor EF1alpha" . J. Proteome Res . 6 (4): 1410–7.
doi :
10.1021/pr060584p .
PMC
4626875 .
PMID
17373842 .