From Wikipedia, the free encyclopedia
Protein-coding gene in the species Homo sapiens
RPS15A Available structures
PDB Ortholog search:
PDBe
RCSB List of PDB id codes
4UG0 ,
4V6X ,
5A2Q ,
5AJ0 ,
4KZY ,
3J7R ,
4D61 ,
4KZX ,
4D5L ,
4V5Z ,
5FLX ,
4UJD ,
3J7P ,
4KZZ ,
4UJE ,
4UJC
Identifiers
Aliases
RPS15A , S15a, ribosomal protein S15a, DBA20External IDs
OMIM :
603674 ;
MGI :
2389091 ;
HomoloGene :
128982 ;
GeneCards :
RPS15A ;
OMA :
RPS15A - orthologs
Wikidata
40S ribosomal protein S15a is a
protein that in humans is encoded by the RPS15A
gene .
[5]
[6]
Ribosomes , the
organelles that
catalyze
protein synthesis , consist of a
small 40S subunit and a
large 60S subunit . Together these subunits are composed of 4
RNA species and approximately 80 structurally distinct proteins. This gene encodes a
ribosomal protein that is a component of the 40S subunit. The protein belongs to the S8P family of ribosomal proteins. It is located in the
cytoplasm . As is typical for genes encoding ribosomal proteins, there are multiple processed
pseudogenes of this gene dispersed through the genome.
[6]
References
^
a
b
c
GRCh38: Ensembl release 89: ENSG00000134419 –
Ensembl , May 2017
^
a
b
c
GRCm38: Ensembl release 89: ENSMUSG00000008683 –
Ensembl , May 2017
^
"Human PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .
^
"Mouse PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .
^ Kenmochi N, Kawaguchi T, Rozen S, Davis E, Goodman N, Hudson TJ, Tanaka T, Page DC (Aug 1998).
"A map of 75 human ribosomal protein genes" . Genome Res . 8 (5): 509–23.
doi :
10.1101/gr.8.5.509 .
PMID
9582194 .
^
a
b
"Entrez Gene: RPS15A ribosomal protein S15a" .
Further reading
Wool IG, Chan YL, Glück A (1996). "Structure and evolution of mammalian ribosomal proteins". Biochem. Cell Biol . 73 (11–12): 933–47.
doi :
10.1139/o95-101 .
PMID
8722009 .
Chan YL, Olvera J, Paz V, Wool IG (1994). "The primary structure of rat ribosomal protein S15a". Biochem. Biophys. Res. Commun . 200 (3): 1498–504.
doi :
10.1006/bbrc.1994.1620 .
PMID
8185605 .
Vladimirov SN, Ivanov AV, Karpova GG, et al. (1996).
"Characterization of the human small-ribosomal-subunit proteins by N-terminal and internal sequencing, and mass spectrometry" . Eur. J. Biochem . 239 (1): 144–9.
doi :
10.1111/j.1432-1033.1996.0144u.x .
PMID
8706699 .
Strausberg RL, Feingold EA, Grouse LH, et al. (2003).
"Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences" . Proc. Natl. Acad. Sci. U.S.A . 99 (26): 16899–903.
Bibcode :
2002PNAS...9916899M .
doi :
10.1073/pnas.242603899 .
PMC
139241 .
PMID
12477932 .
Lehner B, Semple JI, Brown SE, et al. (2004). "Analysis of a high-throughput yeast two-hybrid system and its use to predict the function of intracellular proteins encoded within the human MHC class III region". Genomics . 83 (1): 153–67.
doi :
10.1016/S0888-7543(03)00235-0 .
PMID
14667819 .
Ota T, Suzuki Y, Nishikawa T, et al. (2004).
"Complete sequencing and characterization of 21,243 full-length human cDNAs" . Nat. Genet . 36 (1): 40–5.
doi :
10.1038/ng1285 .
PMID
14702039 .
Gerhard DS, Wagner L, Feingold EA, et al. (2004).
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)" . Genome Res . 14 (10B): 2121–7.
doi :
10.1101/gr.2596504 .
PMC
528928 .
PMID
15489334 .
Yu Y, Ji H, Doudna JA, Leary JA (2005).
"Mass spectrometric analysis of the human 40S ribosomal subunit: native and HCV IRES-bound complexes" . Protein Sci . 14 (6): 1438–46.
doi :
10.1110/ps.041293005 .
PMC
2253395 .
PMID
15883184 .
Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature . 437 (7062): 1173–8.
Bibcode :
2005Natur.437.1173R .
doi :
10.1038/nature04209 .
PMID
16189514 .
S2CID
4427026 .