From Wikipedia, the free encyclopedia
Chemical compound
Thiobutabarbital
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Other names | Thiobutabarbital, Inactin, Brevinarcon, 5-sec-Butyl-5-ethyl-2-thiobarbituric acid |
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ATC code | |
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5-sec-butyl-5-ethyl-2-thioxodihydropyrimidine-4,6(1H,5H)-dione
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CAS Number | |
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PubChem
CID | |
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ChemSpider | |
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UNII | |
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CompTox Dashboard (
EPA) | |
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ECHA InfoCard |
100.016.600
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Formula | C10H16N2O2S |
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Molar mass | 228.31 g·mol−1 |
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3D model (
JSmol) | |
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O=C1NC(=S)NC(=O)C1(C(C)CC)CC
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InChI=1S/C10H16N2O2S/c1-4-6(3)10(5-2)7(13)11-9(15)12-8(10)14/h6H,4-5H2,1-3H3,(H2,11,12,13,14,15) YKey:IDELNEDBPWKHGK-UHFFFAOYSA-N Y
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NY
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Thiobutabarbital (Inactin, Brevinarcon) is a short-acting
barbiturate derivative invented in the 1950s. It has
sedative,
anticonvulsant and
hypnotic effects, and is still used in
veterinary medicine for induction in
surgical
anaesthesia.
[1]
Stereochemistry
Thiobutabarbital contains a stereocenter and consists of two enantiomers. This is a
racemate, i.e. a 1: 1 mixture of ( R ) - and the ( S ) - form:
[2]
Enantiomers of Thiobutabarbital
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(R)-Form
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(S)-Form
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References
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Alcohols | |
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Barbiturates | |
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Benzodiazepines | |
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Carbamates | |
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Flavonoids | |
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Imidazoles | |
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Kava constituents | |
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Monoureides | |
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Neuroactive steroids | |
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Nonbenzodiazepines | |
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Phenols | |
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Piperidinediones | |
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Pyrazolopyridines | |
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Quinazolinones | |
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Volatiles/
gases | |
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Others/unsorted |
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3-Hydroxybutanal
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α-EMTBL
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AA-29504
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Alogabat
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Avermectins (e.g.,
ivermectin)
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Bromide compounds (e.g.,
lithium bromide,
potassium bromide,
sodium bromide)
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Carbamazepine
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Chloralose
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Chlormezanone
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Clomethiazole
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Darigabat
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DEABL
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Deuterated etifoxine
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Dihydroergolines (e.g.,
dihydroergocryptine,
dihydroergosine,
dihydroergotamine,
ergoloid (dihydroergotoxine))
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DS2
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Efavirenz
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Etazepine
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Etifoxine
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Fenamates (e.g.,
flufenamic acid,
mefenamic acid,
niflumic acid,
tolfenamic acid)
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Fluoxetine
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Flupirtine
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Hopantenic acid
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KRM-II-81
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Lanthanum
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Lavender oil
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Lignans (e.g.,
4-O-methylhonokiol,
honokiol,
magnolol,
obovatol)
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Loreclezole
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Menthyl isovalerate (validolum)
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Monastrol
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Niacin
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Niacinamide
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Org 25,435
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Phenytoin
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Propanidid
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Retigabine (ezogabine)
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Safranal
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Seproxetine
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Stiripentol
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Sulfonylalkanes (e.g.,
sulfonmethane (sulfonal),
tetronal,
trional)
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Terpenoids (e.g.,
borneol)
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Topiramate
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Valerian constituents (e.g.,
isovaleric acid,
isovaleramide,
valerenic acid,
valerenol)
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