Small Cajal body specific RNA 4 | |
---|---|
Identifiers | |
Symbol | SCARNA4 |
Alt. Symbols | snoACA26 |
Rfam | RF00423 |
Other data | |
RNA type | Gene; snRNA; snoRNA; scaRNA |
Domain(s) | Eukaryota |
GO | GO:0006396 GO:0015030 GO:0005730 |
SO | SO:0000275 |
PDB structures | PDBe |
In molecular biology, small Cajal body specific RNA 4 (also known as ACA26) is believed to be a guide RNA of the H/ACA box class, since it has the predicted hairpin-hinge-hairpin-tail structure, conserved H/ACA-box motifs, and is found associated with GAR1. [1] In particular, ACA26 is predicted to guide the pseudouridylation of residues U39 and U41 in U2 snRNA. [1] Such scaRNAs are a specific class of small nuclear RNAs that localise to the Cajal bodies and guide the modification of RNA polymerase II transcribed spliceosomal RNAs U1, U2, U4, U5 and U12. [2]