From Wikipedia, the free encyclopedia
InterPro Family
There are three known
mammalian
tachykinin receptors termed NK1, NK2 and NK3. All are members of the
7 transmembrane
G-protein coupled receptor family and induce the activation of
phospholipase C, producing
inositol triphosphate (so called Gq-coupled).
Inhibitors of NK-1, known as
NK-1 receptor antagonists, can be used as
antiemetic agents, such as the drug
aprepitant.
[1]
Binding
The genes and receptor ligands are as follows:
[2]
(
Hökfelt et al., 2001; Page, 2004; Pennefather et al., 2004; Maggi, 2000)
See also
References
External links