From Wikipedia, the free encyclopedia
Protein-coding gene in the species Homo sapiens
Lysophosphatidic acid receptor 5 also known as LPA5 is a
protein that in humans is encoded by the LPAR5
gene.
[5]
[6]
[7]
[8]
[9] LPA5 is a
G protein-coupled receptor that binds the lipid signaling molecule
lysophosphatidic acid (LPA).
[10]
See also
References
- ^
a
b
c
GRCh38: Ensembl release 89: ENSG00000184574 –
Ensembl, May 2017
- ^
a
b
c
GRCm38: Ensembl release 89: ENSMUSG00000067714 –
Ensembl, May 2017
-
^
"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
-
^
"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
-
^ White, Kenneth E.; Evans, Wayne E.; O'Riordan, Jeffery L.H.; Speer, Marcy C.; Econs, Michael J.; Lorenz-Depiereux, Bettina; Grabowski, Monika; Meitinger, Thomas; Strom, Tim M. (Dec 2000). "Autosomal dominant hypophosphataemic rickets is associated with mutations in FGF23". Nat Genet. 26 (3): 345–8.
doi:
10.1038/81664.
PMID
11062477.
S2CID
38870810.
-
^ Lee DK, Nguyen T, Lynch KR, Cheng R, Vanti WB, Arkhitko O, Lewis T, Evans JF, George SR, O'Dowd BF (Sep 2001). "Discovery and mapping of ten novel G protein-coupled receptor genes". Gene. 275 (1): 83–91.
doi:
10.1016/S0378-1119(01)00651-5.
PMID
11574155.
-
^ Lee CW, Rivera R, Gardell S, Dubin AE, Chun J (Aug 2006).
"GPR92 as a new G12/13- and Gq-coupled lysophosphatidic acid receptor that increases cAMP, LPA5". J Biol Chem. 281 (33): 23589–97.
doi:
10.1074/jbc.M603670200.
PMID
16774927.
-
^ Kotarsky K, Boketoft A, Bristulf J, Nilsson NE, Norberg A, Hansson S, Owman C, Sillard R, Leeb-Lundberg LM, Olde B (Jul 2006). "Lysophosphatidic acid binds to and activates GPR92, a G protein-coupled receptor highly expressed in gastrointestinal lymphocytes". J Pharmacol Exp Ther. 318 (2): 619–28.
doi:
10.1124/jpet.105.098848.
PMID
16651401.
S2CID
5989815.
-
^
"Entrez Gene: GPR92 G protein-coupled receptor 92".
-
^ Choi JW, Herr DR, Noguchi K, Yung YC, Lee CW, Mutoh T, Lin ME, Teo ST, Park KE, Mosley AN, Chun J (January 2010). "LPA Receptors: Subtypes and Biological Actions". Annual Review of Pharmacology and Toxicology. 50 (1): 157–186.
doi:
10.1146/annurev.pharmtox.010909.105753.
PMID
20055701.
Further reading