This enzyme belongs to the family of
transferases, specifically those transferring phosphorus-containing
nucleotide groups (
nucleotidyltransferases).op The
systematic name of this enzyme class is GTP:mRNA guanylyltransferase. Other names in common use include mRNA capping enzyme, messenger RNA guanylyltransferase, and Protein 2.
Structural studies
As of late 2007, 5
structures have been solved for this class of enzymes, with
PDB accession codes
1CKM,
1CKN,
1CKO,
1P16, and
2C46.
Groner Y, Gilboa E, Aviv H (1978). "Methylation and capping of RNA polymerase II primary transcripts by HeLa nuclear homogenates". Biochemistry. 17 (6): 977–82.
doi:
10.1021/bi00599a005.
PMID629955.