From Wikipedia, the free encyclopedia
Chemical compound
Estrone tetraacetylglucoside
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[(2R,3R,4S,5R,6S)-3,4,5-triacetyloxy-6-{[(8R,9S,13S,14S)-13-methyl-17-oxo-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-3-yl]oxy}oxan-2-yl]methyl acetate
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CAS Number | |
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PubChem
CID | |
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ChemSpider | |
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CompTox Dashboard (
EPA) | |
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Formula | C32H40O11 |
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Molar mass | 600.661 g·mol−1 |
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3D model (
JSmol) | |
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CC(=O)OCC1OC(Oc2ccc3C4CCC5(C)C(CCC5=O)C4CCc3c2)C(OC(C)=O)C(OC(C)=O)C1OC(C)=O
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InChI=1S/C32H40O11/c1-16(33)38-15-26-28(39-17(2)34)29(40-18(3)35)30(41-19(4)36)31(43-26)42-21-7-9-22-20(14-21)6-8-24-23(22)12-13-32(5)25(24)10-11-27(32)37/h7,9,14,23-26,28-31H,6,8,10-13,15H2,1-5H3 Key:IMZSXCARTLIDBP-UHFFFAOYSA-N
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Estrone tetraacetylglucoside (brand name Glucovex, Glycovex) is a
semisynthetic,
steroidal
estrogen.
[1] It is an
estrogen ester, specifically, an
ester of
estrone.
[1] The drug was marketed since at least 1942.
[2]
References
|
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Estrogens |
ERTooltip Estrogen receptor agonists |
- Steroidal:
Alfatradiol
- Certain
androgens/
anabolic steroids (e.g.,
testosterone,
testosterone esters,
methyltestosterone,
metandienone,
nandrolone esters) (via estrogenic metabolites)
- Certain
progestins (e.g.,
norethisterone,
noretynodrel,
etynodiol diacetate,
tibolone)
-
Clomestrone
-
Cloxestradiol acetate
-
Conjugated estriol
-
Conjugated estrogens
-
Epiestriol
-
Epimestrol
-
Esterified estrogens
-
Estetrol†
-
Estradiol
-
Estradiol esters (e.g.,
estradiol acetate,
estradiol benzoate,
estradiol cypionate,
estradiol enanthate,
estradiol undecylate,
estradiol valerate,
polyestradiol phosphate,
estradiol ester mixtures (
Climacteron))
-
Estramustine phosphate
-
Estriol
-
Estriol esters (e.g.,
estriol succinate,
polyestriol phosphate)
-
Estrogenic substances
-
Estrone
-
Estrone esters
-
Ethinylestradiol#
-
Hydroxyestrone diacetate
-
Mestranol
-
Methylestradiol
-
Moxestrol
-
Nilestriol
-
Prasterone (dehydroepiandrosterone; DHEA)
-
Promestriene
-
Quinestradol
-
Quinestrol
|
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Progonadotropins | |
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|
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Antiestrogens |
ERTooltip Estrogen receptor antagonists (incl.
SERMsTooltip selective estrogen receptor modulators/
SERDsTooltip selective estrogen receptor downregulators) | |
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Aromatase inhibitors | |
---|
Antigonadotropins |
-
Androgens/
anabolic steroids (e.g.,
testosterone,
testosterone esters,
nandrolone esters,
oxandrolone,
fluoxymesterone)
-
D2 receptor
antagonists (
prolactin releasers) (e.g.,
domperidone,
metoclopramide,
risperidone,
haloperidol,
chlorpromazine,
sulpiride)
-
GnRH agonists (e.g.,
leuprorelin,
goserelin)
-
GnRH antagonists (e.g.,
cetrorelix,
elagolix)
-
Progestogens (e.g.,
chlormadinone acetate,
cyproterone acetate,
gestonorone caproate,
hydroxyprogesterone caproate,
medroxyprogesterone acetate,
megestrol acetate)
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Others | |
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|
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ERTooltip Estrogen receptor | Agonists |
- Steroidal:
2-Hydroxyestradiol
-
2-Hydroxyestrone
-
3-Methyl-19-methyleneandrosta-3,5-dien-17β-ol
-
3α-Androstanediol
-
3α,5α-Dihydrolevonorgestrel
-
3β,5α-Dihydrolevonorgestrel
-
3α-Hydroxytibolone
-
3β-Hydroxytibolone
-
3β-Androstanediol
-
4-Androstenediol
-
4-Androstenedione
-
4-Fluoroestradiol
-
4-Hydroxyestradiol
-
4-Hydroxyestrone
-
4-Methoxyestradiol
-
4-Methoxyestrone
-
5-Androstenediol
-
7-Oxo-DHEA
-
7α-Hydroxy-DHEA
-
7α-Methylestradiol
-
7β-Hydroxyepiandrosterone
-
8,9-Dehydroestradiol
-
8,9-Dehydroestrone
-
8β-VE2
-
10β,17β-Dihydroxyestra-1,4-dien-3-one (DHED)
-
11β-Chloromethylestradiol
-
11β-Methoxyestradiol
-
15α-Hydroxyestradiol
-
16-Ketoestradiol
-
16-Ketoestrone
-
16α-Fluoroestradiol
-
16α-Hydroxy-DHEA
-
16α-Hydroxyestrone
-
16α-Iodoestradiol
-
16α-LE2
-
16β-Hydroxyestrone
-
16β,17α-Epiestriol (16β-hydroxy-17α-estradiol)
-
17α-Estradiol (
alfatradiol)
-
17α-Dihydroequilenin
-
17α-Dihydroequilin
-
17α-Epiestriol (16α-hydroxy-17α-estradiol)
-
17α-Ethynyl-3α-androstanediol
-
17α-Ethynyl-3β-androstanediol
-
17β-Dihydroequilenin
-
17β-Dihydroequilin
-
17β-Methyl-17α-dihydroequilenin
-
Abiraterone
-
Abiraterone acetate
-
Alestramustine
-
Almestrone
-
Anabolic steroids (e.g.,
testosterone and
esters,
methyltestosterone,
metandienone (methandrostenolone),
nandrolone and
esters, many others; via estrogenic metabolites)
-
Atrimustine
-
Bolandiol
-
Bolandiol dipropionate
-
Butolame
-
Clomestrone
-
Cloxestradiol
-
Conjugated estriol
-
Conjugated estrogens
-
Cyclodiol
-
Cyclotriol
-
DHEA
-
DHEA-S
-
ent-Estradiol
-
Epiestriol (16β-epiestriol, 16β-hydroxy-17β-estradiol)
-
Epimestrol
-
Equilenin
-
Equilin
-
ERA-63 (ORG-37663)
-
Esterified estrogens
-
Estetrol
-
Estradiol
-
Estramustine
-
Estramustine phosphate
-
Estrapronicate
-
Estrazinol
-
Estriol
-
Estrofurate
-
Estrogenic substances
-
Estromustine
-
Estrone
-
Etamestrol (eptamestrol)
-
Ethinylandrostenediol
-
Ethinylestradiol
-
Ethinylestriol
-
Ethylestradiol
-
Etynodiol
-
Etynodiol diacetate
-
Hexolame
-
Hippulin
-
Hydroxyestrone diacetate
-
Lynestrenol
-
Lynestrenol phenylpropionate
-
Mestranol
-
Methylestradiol
-
Moxestrol
-
Mytatrienediol
-
Nilestriol
-
Norethisterone
-
Noretynodrel
-
Orestrate
-
Pentolame
-
Prodiame
-
Prolame
-
Promestriene
-
RU-16117
-
Quinestradol
-
Quinestrol
-
Tibolone
- Xenoestrogens:
Anise-related (e.g.,
anethole,
anol,
dianethole,
dianol,
photoanethole)
-
Chalconoids (e.g.,
isoliquiritigenin,
phloretin,
phlorizin (phloridzin),
wedelolactone)
-
Coumestans (e.g.,
coumestrol,
psoralidin)
-
Flavonoids (incl.
7,8-DHF,
8-prenylnaringenin,
apigenin,
baicalein,
baicalin,
biochanin A,
calycosin,
catechin,
daidzein,
daidzin,
ECG,
EGCG,
epicatechin,
equol,
formononetin,
glabrene,
glabridin,
genistein,
genistin,
glycitein,
kaempferol,
liquiritigenin,
mirificin,
myricetin,
naringenin,
penduletin,
pinocembrin,
prunetin,
puerarin,
quercetin,
tectoridin,
tectorigenin)
-
Lavender oil
-
Lignans (e.g.,
enterodiol,
enterolactone,
nyasol (cis-hinokiresinol))
-
Metalloestrogens (e.g.,
cadmium)
-
Pesticides (e.g.,
alternariol,
dieldrin,
endosulfan,
fenarimol,
HPTE,
methiocarb,
methoxychlor,
triclocarban,
triclosan)
-
Phytosteroids (e.g.,
digitoxin (
digitalis),
diosgenin,
guggulsterone)
-
Phytosterols (e.g.,
β-sitosterol,
campesterol,
stigmasterol)
-
Resorcylic acid lactones (e.g.,
zearalanone,
α-zearalenol,
β-zearalenol,
zearalenone,
zeranol (α-zearalanol),
taleranol (teranol, β-zearalanol))
-
Steroid-like (e.g.,
deoxymiroestrol,
miroestrol)
-
Stilbenoids (e.g.,
resveratrol,
rhaponticin)
-
Synthetic xenoestrogens (e.g.,
alkylphenols,
bisphenols (e.g.,
BPA,
BPF,
BPS),
DDT,
parabens,
PBBs,
PHBA,
phthalates,
PCBs)
- Others (e.g.,
agnuside,
rotundifuran)
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Mixed (
SERMsTooltip Selective estrogen receptor modulators) | |
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Antagonists |
- Coregulator-binding modulators:
ERX-11
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GPERTooltip G protein-coupled estrogen receptor | Agonists | |
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Antagonists | |
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Unknown | |
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