D-glycero-beta-D-manno-heptose-7-phosphate kinase (
EC2.7.1.167, heptose 7-phosphate kinase, D-beta-D-heptose 7-phosphotransferase, D-beta-D-heptose-7-phosphate kinase, HldE1 heptokinase, glycero-manno-heptose 7-phosphate kinase, D-beta-D-heptose 7-phosphate kinase/D-beta-D-heptose 1-phosphate adenylyltransferase, hldE (gene), rfaE (gene)) is an
enzyme with
systematic nameATP:D-glycero-beta-D-manno-heptose 7-phosphate 1-phosphotransferase.[1][2][3][4][5] This enzyme
catalyses the following
chemical reaction
D-glycero-beta-D-manno-heptose 7-phosphate + ATP D-glycero-beta-D-manno-heptose 1,7-bisphosphate + ADP
The bifunctional protein hldE includes D-glycero-beta-D-manno-heptose-7-phosphate kinase and D-glycero-beta-D-manno-heptose 1-phosphate adenylyltransferase activity (cf.
EC 2.7.7.70).
^Jin UH, Chung TW, Lee YC, Ha SD, Kim CH (October 2001). "Molecular cloning and functional expression of the rfaE gene required for lipopolysaccharide biosynthesis in Salmonella typhimurium". Glycoconjugate Journal. 18 (10): 779–87.
PMID12441667.