From Wikipedia, the free encyclopedia
Enzyme
Anhydro-N-acetylmuramic acid kinase (
EC
2.7.1.170, anhMurNAc kinase, AnmK) is an
enzyme with
systematic name ATP:1,6-anhydro-N-acetyl-beta-muramate 6-phosphotransferase.
[1]
[2]
[3] This enzyme
catalyses the following
chemical reaction
- ATP + 1,6-anhydro-N-acetyl-beta-muramate + H2O
ADP + N-acetylmuramate 6-phosphate
This enzyme is required for the use of anhydro-
N-acetylmuramic acid in
Pseudomonadota.
References
-
^ Uehara T, Suefuji K, Valbuena N, Meehan B, Donegan M, Park JT (June 2005).
"Recycling of the anhydro-N-acetylmuramic acid derived from cell wall murein involves a two-step conversion to N-acetylglucosamine-phosphate". Journal of Bacteriology. 187 (11): 3643–9.
doi:
10.1128/jb.187.11.3643-3649.2005.
PMC
1112033.
PMID
15901686.
-
^ Uehara T, Suefuji K, Jaeger T, Mayer C, Park JT (February 2006).
"MurQ Etherase is required by Escherichia coli in order to metabolize anhydro-N-acetylmuramic acid obtained either from the environment or from its own cell wall". Journal of Bacteriology. 188 (4): 1660–2.
doi:
10.1128/jb.188.4.1660-1662.2006.
PMC
1367226.
PMID
16452451.
-
^ Bacik JP, Whitworth GE, Stubbs KA, Yadav AK, Martin DR, Bailey-Elkin BA, Vocadlo DJ, Mark BL (April 2011).
"Molecular basis of 1,6-anhydro bond cleavage and phosphoryl transfer by Pseudomonas aeruginosa 1,6-anhydro-N-acetylmuramic acid kinase". The Journal of Biological Chemistry. 286 (14): 12283–91.
doi:
10.1074/jbc.m110.198317.
PMC
3069431.
PMID
21288904.
External links
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