Denopamine (
INN) is a cardiotonic drug which acts as a
β1 adrenergic receptoragonist.[1] It is used in the treatment of
angina[2] and may also have potential uses in the treatment of
congestive heart failure[3] and for clearing
pulmonary oedema.[4] It is marketed in Japan under the brand name Kalgut (カルグート) and available as tablets of 5 and 10 mg, and 5% fine granules.[5]
^Nakajima D, Negoro N, Nakaboh A, Nakakoji T, Hoshiga M, Nariyama J, et al. (April 2006). "Effectiveness of low dose denopamine, a beta1-adrenoceptor agonist, in a patient with vasospastic angina refractory to intensive medical treatment". International Journal of Cardiology. 108 (2): 281–3.
doi:
10.1016/j.ijcard.2005.03.012.
PMID15913812.
^Nishio R, Matsumori A, Shioi T, Wang W, Yamada T, Ono K, Sasayama S (September 1998). "Denopamine, a beta1-adrenergic agonist, prolongs survival in a murine model of congestive heart failure induced by viral myocarditis: suppression of tumor necrosis factor-alpha production in the heart". Journal of the American College of Cardiology. 32 (3): 808–15.
doi:
10.1016/S0735-1097(98)00314-3.
hdl:2433/181223.
PMID9741531.