From Wikipedia, the free encyclopedia
NS-398
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Names
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Preferred IUPAC name
N-[2-(Cyclohexyloxy)-4-nitrophenyl]methanesulfonamide
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Identifiers
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ChEBI
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ChEMBL
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ChemSpider
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DrugBank
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InChI=1S/C13H18N2O5S/c1-21(18,19)14-12-8-7-10(15(16)17)9-13(12)20-11-5-3-2-4-6-11/h7-9,11,14H,2-6H2,1H3 YKey: KTDZCOWXCWUPEO-UHFFFAOYSA-N NInChI=1/C13H18N2O5S/c1-21(18,19)14-12-8-7-10(15(16)17)9-13(12)20-11-5-3-2-4-6-11/h7-9,11,14H,2-6H2,1H3 Key: KTDZCOWXCWUPEO-UHFFFAOYAY
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CS(=O)(=O)NC1=C(C=C(C=C1)[N+](=O)[O-])OC2CCCCC2
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Properties
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C13H18N2O5S
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Molar mass
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314.36 g·mol−1
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Appearance
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Off-white solid
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Insoluble
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Solubility in
DMSO
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5 mg/mL
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Hazards
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GHS labelling:
[1]
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Warning
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H302,
H312,
H332
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P280
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Except where otherwise noted, data are given for materials in their
standard state (at 25 °C [77 °F], 100 kPa).
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Chemical compound
NS-398 is a
COX-2 inhibitor used in the study of the function of
cyclooxygenases.
[2]
See also
References
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Receptor (
ligands) |
DP (D2)Tooltip Prostaglandin D2 receptor |
DP1Tooltip Prostaglandin D2 receptor 1 | |
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DP2Tooltip Prostaglandin D2 receptor 2 | |
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EP (E2)Tooltip Prostaglandin E2 receptor |
EP1Tooltip Prostaglandin EP1 receptor | |
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EP2Tooltip Prostaglandin EP2 receptor | |
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EP3Tooltip Prostaglandin EP3 receptor | |
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EP4Tooltip Prostaglandin EP4 receptor | |
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Unsorted | |
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FP (F2α)Tooltip Prostaglandin F receptor | |
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IP (I2)Tooltip Prostacyclin receptor | |
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TP (TXA2)Tooltip Thromboxane receptor | |
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Unsorted | |
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Enzyme (
inhibitors) |
COX (
PTGS) | |
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PGD2STooltip Prostaglandin D synthase | |
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PGESTooltip Prostaglandin E synthase | |
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PGFSTooltip Prostaglandin F synthase | |
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PGI2STooltip Prostacyclin synthase | |
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TXASTooltip Thromboxane A synthase | |
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Others | |
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