From Wikipedia, the free encyclopedia
Chemical compound
Metacycline
![](https://upload.wikimedia.org/wikipedia/commons/thumb/c/c5/Metacycline.svg/220px-Metacycline.svg.png) |
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AHFS/
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International Drug Names |
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ATC code | |
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(2Z,4S,4aR,5S,5aR,12aS)-2-[amino(hydroxy)methylene]-4-(dimethylamino)-5,10,11,12a-tetrahydroxy-6-methylene-4a,5a,6,12a-tetrahydrotetracene-1,3,12(2H,4H,5H)-trione
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PubChem
CID | |
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ChemSpider | |
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UNII | |
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ChEMBL | |
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NIAID ChemDB | |
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CompTox Dashboard (
EPA) | |
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ECHA InfoCard |
100.011.834
![Edit this at Wikidata](https://upload.wikimedia.org/wikipedia/en/thumb/8/8a/OOjs_UI_icon_edit-ltr-progressive.svg/10px-OOjs_UI_icon_edit-ltr-progressive.svg.png) |
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Formula | C22H22N2O8 |
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Molar mass | 442.424 g·mol−1 |
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3D model (
JSmol) | |
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NC(=O)C=3C(=O)[C@@]4(O)C(\O)=C2\C(=O)c1c(O)cccc1C(=C)[C@H]2[C@H](O)[C@H]4[C@H](N(C)C)C=3O
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InChI=1S/C22H22N2O8/c1-7-8-5-4-6-9(25)11(8)16(26)12-10(7)17(27)14-15(24(2)3)18(28)13(21(23)31)20(30)22(14,32)19(12)29/h4-6,10,14-15,17,25,27-29,32H,1H2,2-3H3,(H2,23,31)/t10-,14-,15+,17+,22+/m1/s1 YKey:MHIGBKBJSQVXNH-IWVLMIASSA-N Y
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(what is this?)
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Metacycline or methacycline is a
tetracycline antibiotic. It is used as a
precursor in the industrial
synthesis of
doxycycline hyclate.[
citation needed]
It has been found to act as an
agonist of the human
pregnane X receptor
ligand-binding domain and to induce
CYP3A4
expression
in vitro.
[1]
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CARTooltip Constitutive androstane receptor | |
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PXRTooltip Pregnane X receptor | |
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