Ioxitalamic Acid

Ioxitalamic acid
Clinical data
AHFS/ Drugs.com	International Drug Names
ATC code	V08AA05 ( WHO) ;
Identifiers
	IUPAC name 3-acetamido-5-[(2-hydroxyethyl)carbamoyl]-2,4,6-triiodobenzoic acid;
CAS Number	28179-44-4;
PubChem CID	34536;
ChemSpider	31782;
UNII	967RDI7Z6K;
KEGG	D07418;
ChEBI	CHEBI:83517 ;
ChEMBL	ChEMBL2107239;
CompTox Dashboard ( EPA)	DTXSID60182457 ;
ECHA InfoCard	100.044.428
Chemical and physical data
Formula	C12H11I3N2O5
Molar mass	643.942 g·mol−1
3D model ( JSmol)	Interactive image;
	SMILES CC(=O)NC1=C(C(=C(C(=C1I)C(=O)O)I)C(=O)NCCO)I;
	InChI InChI=1S/C12H11I3N2O5/c1-4(19)17-10-8(14)5(11(20)16-2-3-18)7(13)6(9(10)15)12(21)22/h18H,2-3H2,1H3,(H,16,20)(H,17,19)(H,21,22); Key:OLAOYPRJVHUHCF-UHFFFAOYSA-N;

Ioxitalamic acid (brand name Telebrix) is a pharmaceutical drug used as an iodinated contrast medium for X-ray imaging.^[1]^[2] It is used in form of its salts, ioxitalamate sodium and ioxitalamate meglumine.^[3]

References

^ Wiggli U (January 1979). "[Clinical study of the tolerance for 2 iodine containing contrast media for computerized tomography of the skull]". Schweizerische Medizinische Wochenschrift. 109 (2): 51–4. PMID 370976.
^ El-Garawani I, Hassab El-Nabi S, El Kattan A, Sallam A, Elballat S, Abou-Ghanima S, et al. (February 2021). "The Ameliorative Role of Acacia senegal Gum against the Oxidative Stress and Genotoxicity Induced by the Radiographic Contrast Medium (Ioxitalamate) in Albino Rats". Antioxidants. 10 (2): 221. doi: 10.3390/antiox10020221. PMC 7912984. PMID 33540787.
^ International Drug Names: Telebrix. Accessed 2021-03-31.

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[1] Wiggli U (January 1979). "[Clinical study of the tolerance for 2 iodine containing contrast media for computerized tomography of the skull]". Schweizerische Medizinische Wochenschrift. 109 (2): 51–4. PMID 370976.

[2] El-Garawani I, Hassab El-Nabi S, El Kattan A, Sallam A, Elballat S, Abou-Ghanima S, et al. (February 2021). "The Ameliorative Role of Acacia senegal Gum against the Oxidative Stress and Genotoxicity Induced by the Radiographic Contrast Medium (Ioxitalamate) in Albino Rats". Antioxidants. 10 (2): 221. doi: 10.3390/antiox10020221. PMC 7912984. PMID 33540787.

[3] International Drug Names: Telebrix. Accessed 2021-03-31.

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Clinical data


AHFS/ Drugs.com	International Drug Names
ATC code	V08AA05 ( WHO)
Identifiers
IUPAC name 3-acetamido-5-[(2-hydroxyethyl)carbamoyl]-2,4,6-triiodobenzoic acid
CAS Number	28179-44-4
PubChem CID	34536
ChemSpider	31782
UNII	967RDI7Z6K
KEGG	D07418
ChEBI	CHEBI:83517^Y
ChEMBL	ChEMBL2107239
CompTox Dashboard ( EPA)	DTXSID60182457
ECHA InfoCard	100.044.428
Chemical and physical data
Formula	C₁₂H₁₁I₃N₂O₅
Molar mass	643.942 g·mol⁻¹
3D model ( JSmol)	Interactive image
SMILES CC(=O)NC1=C(C(=C(C(=C1I)C(=O)O)I)C(=O)NCCO)I
InChI InChI=1S/C12H11I3N2O5/c1-4(19)17-10-8(14)5(11(20)16-2-3-18)7(13)6(9(10)15)12(21)22/h18H,2-3H2,1H3,(H,16,20)(H,17,19)(H,21,22) Key:OLAOYPRJVHUHCF-UHFFFAOYSA-N