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glycolate dehydrogenase
Identifiers
EC no. 1.1.99.14
CAS no. 37368-32-4
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum
Gene Ontology AmiGO / QuickGO
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PMC articles
PubMed articles
NCBI proteins

In enzymology, a glycolate dehydrogenase ( EC 1.1.99.14) is an enzyme that catalyzes the chemical reaction

glycolate + acceptor glyoxylate + reduced acceptor

Thus, the two substrates of this enzyme are glycolate and acceptor, whereas its two products are glyoxylate and reduced acceptor.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with other acceptors. The systematic name of this enzyme class is glycolate:acceptor 2-oxidoreductase. Other names in common use include glycolate oxidoreductase, glycolic acid dehydrogenase, and glycolate:(acceptor) 2-oxidoreductase. This enzyme participates in glyoxylate and dicarboxylate metabolism.

References

  • Lord JM (May 1972). "Glycolate oxidoreductase in Escherichia coli". Biochimica et Biophysica Acta (BBA) - Bioenergetics. 267 (2): 227–37. doi: 10.1016/0005-2728(72)90111-9. PMID  4557653.