It belongs to the family of
hydrolases, specifically those glycosidases that hydrolyse O- and S-glycosyl compounds. The
systematic name of this enzyme class is cyclomaltodextrin dextrin-hydrolase (decyclizing). Other names in common use include cycloheptaglucanase, cyclohexaglucanase, and cyclodextrinase. The enzyme participates in
starch and
sucrosemetabolism and
acarbose degradation.[1][2] The cyclomaltodextrinase is capable of degradation of
acarbose to glucose and acarviosine-glucose.[3]
Structural studies
As of late 2007, two
structures have been solved for this class of enzymes, with
PDB accession codes
1EA9 and
1H3G.
References
^Jang MU, Jeong CK, Kang HJ, Kim MJ, Lee MJ, Son BS, Kim TJ (2016). "Gene Cluster Analysis and Functional Characterization of Cyclomaltodextrinase from Listeria innocua". Microbiology and Biotechnology Letters. 44 (3): 363–369.
doi:
10.4014/mbl.1608.08008.
ISSN1598-642X.
^Jang MU, Kang HJ, Jeong CK, Kang Y, Park JE, Kim TJ (February 2018). "Functional expression and enzymatic characterization of Lactobacillus plantarum cyclomaltodextrinase catalyzing novel acarbose hydrolysis". Journal of Microbiology. 56 (2): 113–118.
doi:
10.1007/s12275-018-7551-3.
PMID29392561.