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CDP-paratose synthase
Identifiers
EC no. 1.1.1.342
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum
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PMC articles
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NCBI proteins

CDP-paratose synthase ( EC 1.1.1.342, rfbS (gene)) is an enzyme with systematic name CDP-alpha-D-paratose:NADP+ 4-oxidoreductase. [1] [2] This enzyme catalyses the following chemical reaction

CDP-alpha-D-paratose + NADP+ CDP-4-dehydro-3,6-dideoxy-alpha-D-glucose + NADPH + H+

This enzyme participates in synthesis of paratose and tyvelose.

References

  1. ^ Verma N, Reeves P (October 1989). "Identification and sequence of rfbS and rfbE, which determine antigenic specificity of group A and group D salmonellae". Journal of Bacteriology. 171 (10): 5694–701. PMC  210416. PMID  2793833.
  2. ^ Hallis TM, Lei Y, Que NL, Liu H (April 1998). "Mechanistic studies of the biosynthesis of paratose: purification and characterization of CDP-paratose synthase". Biochemistry. 37 (14): 4935–45. doi: 10.1021/bi9725529. PMID  9538012.

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