Troxerutin has been shown in mice to reverse CNS insulin resistance and reduce
reactive oxygen species induced by a high-cholesterol diet.[3]
References
^Zhang ZF, Fan SH, Zheng YL, Lu J, Wu DM, Shan Q, Hu B (September 2014). "Troxerutin improves hepatic lipid homeostasis by restoring NAD(+)-depletion-mediated dysfunction of lipin 1 signaling in high-fat diet-treated mice". Biochemical Pharmacology. 91 (1): 74–86.
doi:
10.1016/j.bcp.2014.07.002.
PMID25026599.
^Riccioni C, Sarcinella R, Izzo A, Palermo G, Liguori M (February 2004). "[Effectiveness of Troxerutin in association with Pycnogenol in the pharmacological treatment of venous insufficiency]". Minerva Cardioangiologica. 52 (1): 43–8.
PMID14765037.