From Wikipedia, the free encyclopedia
Combretol
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Names
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IUPAC name
5-Hydroxy-3,3′,4′,5′,7-pentamethoxyflavone
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Preferred IUPAC name
5-Hydroxy-3,7-dimethoxy-2-(3,4,5-trimethoxyphenyl)-4H-1-benzopyran-4-one
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Other names
3,7,3',4',5'-pentamethylmyricetin
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Identifiers
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ChEBI
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ChEMBL
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ChemSpider
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UNII
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InChI=1S/C20H20O8/c1-23-11-8-12(21)16-13(9-11)28-18(20(27-5)17(16)22)10-6-14(24-2)19(26-4)15(7-10)25-3/h6-9,21H,1-5H3 NKey: SUNUQCQIFHHEOW-UHFFFAOYSA-N NInChI=1/C20H20O8/c1-23-11-8-12(21)16-13(9-11)28-18(20(27-5)17(16)22)10-6-14(24-2)19(26-4)15(7-10)25-3/h6-9,21H,1-5H3 Key: SUNUQCQIFHHEOW-UHFFFAOYAT
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COC1=CC(=C2C(=C1)OC(=C(C2=O)OC)C3=CC(=C(C(=C3)OC)OC)OC)O
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Properties
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C20H20O8
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Molar mass
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388.36 g/mol
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Except where otherwise noted, data are given for materials in their
standard state (at 25 °C [77 °F], 100 kPa).
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Chemical compound
Combretol is an
O-methylated flavonol, a type of flavonoid. It is the 3,7,3',4',5'-O-methylation of
myricetin and can be extracted from
Combretum quadrangulare
[2] and from
Rhodomyrtus tomentosa.
[3]
References
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^
"KNApSAcK Metabolite Information - C00004777". www.knapsackfamily.com.
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^ Combretol from Combretum quadrangulare. Stang Mongkolsuk, F. M. Dean and L. E. Houghton, J. Chem. Soc. C, 1966, page 125,
doi:
10.1039/J39660000125
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^
5-Hydroxy-3,3',4',5',7-pentamethoxyflavone (combretol). Dachriyanus, R. Fahmi, M. V. Sargent, B. W. Skelton and A. H. White, Acta Crystallogr. (2004). E60, o86-o88
Flavonols and their conjugates |
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Backbone | |
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Flavonols | |
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O-Methylated flavonols | |
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Derivative flavonols | |
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Pyranoflavonols | |
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Furanoflavonols | |
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Semisynthetic | |
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