From Wikipedia, the free encyclopedia
Class of enzymes
Trans,polycis-decaprenyl diphosphate synthase (
EC
2.5.1.86 , Rv2361c , (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E)-decaprenyl diphosphate synthase ) is an
enzyme with
systematic name (2Z,6E)-farnesyl-diphosphate:isopentenyl-diphosphate farnesylcistransferase (adding 7 isopentenyl units) .
[1]
[2]
[3] This enzyme
catalyses the following
chemical reaction
(2Z,6E)-farnesyl diphosphate + 7
isopentenyl diphosphate
⇌
{\displaystyle \rightleftharpoons }
7
diphosphate + trans,octacis-decaprenyl diphosphate
The enzyme is involved in the biosynthesis of
decaprenyl phosphate .
References
^ Kaur D, Brennan PJ, Crick DC (November 2004).
"Decaprenyl diphosphate synthesis in Mycobacterium tuberculosis" . Journal of Bacteriology . 186 (22): 7564–70.
doi :
10.1128/JB.186.22.7564-7570.2004 .
PMC
524883 .
PMID
15516568 .
^ Wang W, Dong C, McNeil M, Kaur D, Mahapatra S, Crick DC, Naismith JH (August 2008).
"The structural basis of chain length control in Rv1086" . Journal of Molecular Biology . 381 (1): 129–40.
doi :
10.1016/j.jmb.2008.05.060 .
PMC
2527485 .
PMID
18597781 .
^ Crick DC, Schulbach MC, Zink EE, Macchia M, Barontini S, Besra GS, Brennan PJ (October 2000).
"Polyprenyl phosphate biosynthesis in Mycobacterium tuberculosis and Mycobacterium smegmatis" . Journal of Bacteriology . 182 (20): 5771–8.
doi :
10.1128/JB.182.20.5771-5778.2000 .
PMC
94699 .
PMID
11004176 .
External links
Activity Regulation Classification Kinetics Types