British bioinformatics researcher
Teresa K. Attwood (born 20 November 1959) is a professor of
Bioinformatics in the
Department of Computer Science and
School of Biological Sciences at the
University of Manchester and a visiting
fellow at the
European Bioinformatics Institute (EMBL-EBI) .
[5] She held a
Royal Society University Research Fellowship at
University College London (UCL) from 1993 to 1999 and at the University of Manchester from 1999 to 2002.
[1]
Education
Attwood gained her
Bachelor of Science in
Biophysics from the
University of Leeds in 1982.
[6] She was awarded a
PhD , also in Biophysics, two years later, in 1984
[2] under the supervision of John E. Lydon
[7] studying chromonic
mesophases .
Research and career
Attwood undertook
postdoctoral research at Leeds until 1993, when she moved to
University College London
[8] for five years before moving to the
University of Manchester in 1999. Her research
[9]
[10] concerns protein
sequence alignment and
protein analysis .
Inspired by the creation of
PROSITE , Attwood developed a method of
protein fingerprinting and used this to establish the
PRINTS
[11]
[12]
[13] database. With
Amos Bairoch she sought to unify work on
protein family classification and annotation, eventually jointly securing a
European Union grant with
Rolf Apweiler to establish
InterPro ,
[14]
[15] with
Pfam , ProDom and
Swiss-Prot/TrEMBL as consortium partners in 1997.
[16]
Attwood has led major projects including the BioMinT
FP5
[17] text-mining consortium, the EMBER
[18] bioinformatics education consortium (including
EBI and
Swiss Institute of Bioinformatics as partners), and the
EPSRC PARADIGM Platform.
[19] She is the Manchester
principal investigator on projects SeqAhead (
Next-generation sequencing data analysis network)
[20] and AllBio (bioinformatics infrastructure for unicellular, animal and plant sciences),
[21] and was also Manchester
PI on EMBRACE
[22] and EuroKUP (kidney and urine proteomics).
[23] Attwood was a member of ELIXIR's Bioinformatics Training Strategy Committee (Work Package 11)
[24] during ELIXIR's preparatory phase. She is currently Chair of the
EMBnet Global Bioinformatics Network, she was a member of the Executive Committees of the
International Society for Biocuration , and the Bioinformatics Training Network, and was recently elected to the Board of Directors of the International Society for Computational Biology. In 2012, she spearheaded the establishment of a GOBLET (Global Organisation for Bioinformatics Learning, Education and Training), with the major bioinformatics, computational biology and biocuration societies, networks and organisations as partners. As of 2016
[update] , Attwood is the Chair of the
GOBLET Executive Board.
[25]
[26]
As well as being a
biocurator
[16]
[27] she has co-developed tools to align and visualise protein sequences and structures, including Ambrosia and CINEMA.
[28]
[29] The group are building re-usable software components to create useful bioinformatics applications through
UTOPIA (Bioinformatics tools) ,
[30]
[31] and are developing new approaches for automatic annotation and
text mining , like PRECIS,
[32] METIS,
[33] BioIE,
[34] and semantic approaches to data integration,
[35] such as the Semantic
Biochemical Journal
[36] published by
Portland Press . The
UTOPIA tools underpin both the Semantic
Biochemical Journal and a collaborative project with
Pfizer and
AstraZeneca to develop a 21st-century interface to biomedical literature and data management.
Attwood's research has received funding from the
Engineering and Physical Sciences Research Council ,
[37] the
Biotechnology and Biological Sciences Research Council , the
Wellcome Trust , the
Royal Society , the
European Union and industry.
[6]
Teaching
Attwood teaches on
undergraduate and
postgraduate courses and has been
doctoral advisor or co-supervisor to several PhD students (e.g.,
Manuel Corpas ). Attwood has co-authored several book chapters and three popular bioinformatics textbooks: Introduction to Bioinformatics
[38] and Bioinformatics and Molecular Evolution .
[39]
Attwood is a co-author of the
bioinformatics textbook Bioinformatics Challenges at the Interface of Biology and Computer Science: Mind the Gap
[40] with
Steve Pettifer and Dave Thorne.
Academic service
Attwood serves on the
editorial board of the
Biochemical Journal ,
[41]
Database: The Journal of Biological Databases and Curation ,
[42] Molecular and Cellular Proteomics ,[
citation needed ] the Journal of Molecular Graphics and Modelling and the EMBnet.journal. [
citation needed ]
Awards and honours
Attwood held a
Royal Society University Research Fellowship (URF) from 1993 to 2002.
[1]
References
^
a
b
c Anon (2016).
"Teresa Attwood Professor of Bioinformatics" . manchester.ac.uk . Manchester. Archived from
the original on 24 December 2016.
^
a
b
Attwood, Teresa K. (1984).
Chromonic mesophases (PhD thesis). University of Leeds.
OCLC
59334329 .
^ Corpas, Manuel (2007). Folding patterns in protein sequences (PhD thesis). University of Manchester.
doi :
10.6084/m9.figshare.964811.v1 .
^
Teresa Attwood at
Library of Congress
^
57193816586 Attwood, Teresa's publications indexed by the
Scopus bibliographic database. (subscription required)
^
a
b Terri Attwood's
ORCID
0000-0003-2409-4235
^
Attwood, T. K. ; Lydon, J. E. (1984). "Lyotropic Mesophase Formation by Anti-Asthmatic Drugs". Molecular Crystals and Liquid Crystals . 108 (3–4): 349.
Bibcode :
1984MCLC..108..349A .
doi :
10.1080/00268948408078686 .
^
"Teresa K Attwood" . biochem.ucl.ac.uk/bsm/dbbrowser .
^
Terri K. Attwood at
DBLP Bibliography Server
^
Terri Attwood publications indexed by
Google Scholar
^
Attwood, T. K. ; Coletta, A.; Muirhead, G.; Pavlopoulou, A.; Philippou, P. B.; Popov, I.; Romá-Mateo, C.; Theodosiou, A.; Mitchell, A. L. (2012).
"The PRINTS database: A fine-grained protein sequence annotation and analysis resource--its status in 2012" . Database . 2012 : bas019.
doi :
10.1093/database/bas019 .
PMC
3326521 .
PMID
22508994 .
^
Attwood, T. K. ; Croning, M. D.; Flower, D. R.; Lewis, A. P.; Mabey, J. E.; Scordis, P.; Selley, J. N.; Wright, W. (2000).
"PRINTS-S: The database formerly known as PRINTS" . Nucleic Acids Research . 28 (1): 225–227.
doi :
10.1093/nar/28.1.225 .
PMC
102408 .
PMID
10592232 .
^
Attwood, T. K. ; Bradley, P.; Flower, D. R.; Gaulton, A.; Maudling, N.; Mitchell, A. L.; Moulton, G.; Nordle, A.; Paine, K.; Taylor, P.; Uddin, A.; Zygouri, C. (2003).
"PRINTS and its automatic supplement, prePRINTS" . Nucleic Acids Research . 31 (1): 400–402.
doi :
10.1093/nar/gkg030 .
PMC
165477 .
PMID
12520033 .
^
Apweiler, R. ;
Attwood, T. K. ;
Bairoch, A. ;
Bateman, A. ;
Birney, E. ; Biswas, M.; Bucher, P.; Cerutti, L.; Corpet, F.; Croning, M. D.;
Durbin, R. ; Falquet, L.; Fleischmann, W.; Gouzy, J.; Hermjakob, H.; Hulo, N.; Jonassen, I.; Kahn, D.; Kanapin, A.; Karavidopoulou, Y.; Lopez, R.; Marx, B.; Mulder, N. J.; Oinn, T. M.; Pagni, M.; Servant, F.; Sigrist, C. J.; Zdobnov, E. M. (2001).
"The InterPro database, an integrated documentation resource for protein families, domains and functional sites" . Nucleic Acids Research . 29 (1): 37–40.
doi :
10.1093/nar/29.1.37 .
PMC
29841 .
PMID
11125043 .
^
Apweiler, R. ;
Attwood, T. K. ;
Bairoch, A. ;
Bateman, A. ;
Birney, E. ; Biswas, M.; Bucher, P.; Cerutti, L.; Corpet, F.; Croning, M. D. R.;
Durbin, R. ; Falquet, L.; Fleischmann, W.; Gouzy, J.; Hermjakob, H.; Hulo, N.; Jonassen, I.; Kahn, D.; Kanapin, A.; Karavidopoulou, Y.; Lopez, R.; Marx, B.; Mulder, N. J.; Oinn, T. M.; Pagni, M.; Servant, F.; Sigrist, C. J. A.; Zdobnov, E. M.; Interpro, C. (2000).
"InterPro--an integrated documentation resource for protein families, domains and functional sites" . Bioinformatics . 16 (12): 1145–1150.
doi :
10.1093/bioinformatics/16.12.1145 .
PMID
11159333 .
^
a
b
http://www.biocurator.org/elec/candidates2011/Attwood.pdf Attwood biography from biocurator.org
^
"BioMinT: Biological Text Mining EU FP5 Quality of Life Project" . Archived from
the original on 19 June 2012.
^
"EMBER - European Multimedia Bioinformatics Educational Resource" . www.bioinf.man.ac.uk .
^
"Platform grant: PARADIGM - Platform for Annotation, Robust Analysis, Data Integration & Genome Management" . Retrieved 25 July 2012 .
^
"COST Action: NGS-Data Analysis Network" . Retrieved 25 July 2012 .
^
"start – AllBio" . Archived from
the original on 29 December 2012.
^ Pettifer, S.; Ison, J.; Kalas, M.; Thorne, D.; McDermott, P.; Jonassen, I.; Liaquat, A.; Fernández, J. M.; Rodriguez, J. M.; Partners, I. -; Pisano, D. G.; Blanchet, C.; Uludag, M.; Rice, P.; Bartaseviciute, E.; Rapacki, K.; Hekkelman, M.; Sand, O.; Stockinger, H.; Clegg, A. B.; Bongcam-Rudloff, E.; Salzemann, J.; Breton, V.; Attwood, T. K.; Cameron, G.; Vriend, G. (2010).
"The EMBRACE web service collection" . Nucleic Acids Research . 38 (Web Server issue): W683–W688.
doi :
10.1093/nar/gkq297 .
PMC
2896104 .
PMID
20462862 .
^
"European Kidney and Urine Proteomics | Eurokup" . Retrieved 25 July 2012 .
^
"Welcome to ELIXIR" . Retrieved 26 July 2012 .
^
"Committees | GOBLET" . www.mygoblet.org . 16 November 2014. Retrieved 24 August 2016 .
^
Corpas, M. ; Jimenez, R. C.;
Bongcam-Rudloff, E. ; Budd, A.; Brazas, M. D.; Fernandes, P. L.; van Gelder, C.; Korpelainen, E.; Lewitter, F.; McGrath, A.; MacLean, D.; Palagi, P.; Rother, K.; Taylor, J.; Via, A.; Watson, M.; Schneider, M. V.; Attwood, T. K. (2015).
"The GOBLET training portal: a global repository of bioinformatics training materials, courses and trainers" . Bioinformatics . 31 (1): 140–142.
doi :
10.1093/bioinformatics/btu601 .
PMC
4271145 .
PMID
25189782 .
^ Burge, S.;
Attwood, T. K. ;
Bateman, A. ; Berardini, T. Z.; Cherry, M.; O'Donovan, C.; Xenarios, L.; Gaudet, P. (2012).
"Biocurators and Biocuration: Surveying the 21st century challenges" . Database . 2012 : bar059.
doi :
10.1093/database/bar059 .
PMC
3308150 .
PMID
22434828 .
^ Lord, P. W.; Selley, J. N.;
Attwood, T. K. (2002).
"CINEMA-MX: A modular multiple alignment editor" . Bioinformatics . 18 (10): 1402–1403.
doi :
10.1093/bioinformatics/18.10.1402 .
PMID
12376388 .
^ Parry-Smith, D. J.; Payne, A. W. R.; Michie, A. D.;
Attwood, T. K. (1998). "CINEMA—a novel Colour INteractive Editor for Multiple Alignments". Gene . 221 (1): GC57–GC63.
doi :
10.1016/S0378-1119(97)00650-1 .
PMID
9852962 .
^
Attwood, T. K. ;
Kell, D. B. ; McDermott, P.; Marsh, J.;
Pettifer, S. R. ; Thorne, D. (2010).
"Utopia documents: Linking scholarly literature with research data" . Bioinformatics . 26 (18): i568–i574.
doi :
10.1093/bioinformatics/btq383 .
PMC
2935404 .
PMID
20823323 .
^
Pettifer, S. R. ; Sinnott, J. R.;
Attwood, T. K. (2004).
"UTOPIA—User-Friendly Tools for Operating Informatics Applications" . Comparative and Functional Genomics . 5 (1): 56–60.
doi :
10.1002/cfg.359 .
PMC
2447318 .
PMID
18629035 .
^ Mitchell, A. L.; Reich, J. R.;
Attwood, T. K. (2003).
"PRECIS: Protein reports engineered from concise information in SWISS-PROT" . Bioinformatics . 19 (13): 1664–1671.
doi :
10.1093/bioinformatics/btg204 .
PMID
12967963 .
^ Mitchell, A. L.; Divoli, A.; Kim, J. -H.; Hilario, M.; Selimas, I.;
Attwood, T. K. (2005).
"METIS: Multiple extraction techniques for informative sentences" . Bioinformatics . 21 (22): 4196–4197.
doi :
10.1093/bioinformatics/bti675 .
PMID
16159915 .
^ Divoli, A.;
Attwood, T. K. (2005). "BioIE: Extracting informative sentences from the biomedical literature". Bioinformatics . 21 (9): 2138–2139.
doi :
10.1093/bioinformatics/bti296 .
PMID
15691860 .
^
Pettifer, S. ; Thorne, D.; McDermott, P.; Marsh, J.; Villéger, A.;
Kell, D. B. ;
Attwood, T. K. (2009).
"Visualising biological data: A semantic approach to tool and database integration" . BMC Bioinformatics . 10 (Suppl 6): S19.
doi :
10.1186/1471-2105-10-S6-S19 .
PMC
2697642 .
PMID
19534744 .
^
Attwood, T. K. ;
Kell, D. B. ; McDermott, P.; Marsh, J.;
Pettifer, S. R. ; Thorne, D. (2009).
"Calling International Rescue: Knowledge lost in literature and data landslide!" . Biochemical Journal . 424 (3): 317–333.
doi :
10.1042/BJ20091474 .
PMC
2805925 .
PMID
19929850 .
^ Anon.
"Grants awarded to Terri Attwood by the EPSRC" . epsrc.ac.uk . Swindon. Retrieved 25 July 2012 .
^ Parry-Smith, David J.; Attwood, Teresa K. (1999). Introduction to bioinformatics . New York: Longman.
ISBN
978-0-582-32788-7 .
^ Attwood, Teresa K.; Higgs, Paul (2005). Bioinformatics And Molecular Evolution . Cambridge, Massachusetts: Blackwell Publishers.
ISBN
978-1-4051-0683-2 .
^ Attwood, Teresa K.; Pettifer, Stephen Robert; Thorne, David (2016).
Bioinformatics Challenges at the Interface of Biology and Computer Science: Mind the Gap . Chichester, West Sussex; Hoboken, New Jersey:
Wiley-Blackwell . p. 424.
ISBN
9780470035481 .
OCLC
951190363 .
^
"Biochemical Journal Editorial Board" . Archived from
the original on 20 February 1999. Retrieved 25 July 2012 .
^
"Oxford Journals | Life Sciences | Database | Editorial board" . Retrieved 25 July 2012 .
International National Academics Other