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TRNA1Val (adenine37-N6)-methyltransferase
Identifiers
EC no. 2.1.1.223
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum
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PMC articles
PubMed articles
NCBI proteins

TRNA1Val (adenine37-N6)-methyltransferase ( EC 2.1.1.223, YfiC) is an enzyme with systematic name S-adenosyl-L-methionine:tRNA1Val (adenine37-N6)-methyltransferase. [1] This enzyme catalyses the following chemical reaction

S-adenosyl-L-methionine + adenine37 in tRNA1Val S-adenosyl-L-homocysteine + N6-methyladenine37 in tRNA1Val

The enzyme specifically methylates adenine37 in tRNA1Val ( anticodon cmo5UAC).

References

  1. ^ Golovina AY, Sergiev PV, Golovin AV, Serebryakova MV, Demina I, Govorun VM, Dontsova OA (June 2009). "The yfiC gene of E. coli encodes an adenine-N6 methyltransferase that specifically modifies A37 of tRNA1Val(cmo5UAC)". RNA. 15 (6): 1134–41. doi: 10.1261/rna.1494409. PMC  2685529. PMID  19383770.

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