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TRNA-guanine15 transglycosylase
Identifiers
EC no. 2.4.2.48
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum
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PMC articles
PubMed articles
NCBI proteins

TRNA-guanine15 transglycosylase ( EC 2.4.2.48, tRNA transglycosylase, transfer ribonucleate glycosyltransferase, tRNA guanine15 transglycosidase, TGT, transfer ribonucleic acid guanine15 transglycosylase) is an enzyme with systematic name tRNA-guanine15:7-cyano-7-carbaguanine tRNA-D-ribosyltransferase. [1] This enzyme catalyses the following chemical reaction

guanine15 in tRNA + 7-cyano-7-carbaguanine 7-cyano-7-carbaguanine15 in tRNA + guanine

Archaeal tRNAs contain the modified nucleoside archaeosine at position 15.

References

  1. ^ Bai Y, Fox DT, Lacy JA, Van Lanen SG, Iwata-Reuyl D (September 2000). "Hypermodification of tRNA in Thermophilic archaea. Cloning, overexpression, and characterization of tRNA-guanine transglycosylase from Methanococcus jannaschii". The Journal of Biological Chemistry. 275 (37): 28731–8. doi: 10.1074/jbc.M002174200. PMID  10862614.

External links