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pyrogallol 1,2-oxygenase
Identifiers
EC no. 1.13.11.35
CAS no. 78310-68-6
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum
Gene Ontology AmiGO / QuickGO
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NCBI proteins

In enzymology, a pyrogallol 1,2-oxygenase ( EC 1.13.11.35) is an enzyme that catalyzes the chemical reaction

1,2,3-trihydroxybenzene + O2 (Z)-5-oxohex-2-enedioate

Thus, the two substrates of this enzyme are 1,2,3-trihydroxybenzene and O2, whereas its product is (Z)-5-oxohex-2-enedioate.

This enzyme belongs to the family of oxidoreductases, specifically those acting on single donors with O2 as oxidant and incorporation of two atoms of oxygen into the substrate (oxygenases). The oxygen incorporated need not be derived from O2. The systematic name of this enzyme class is 1,2,3-trihydroxybenzene:oxygen 1,2-oxidoreductase (decyclizing). This enzyme is also called pyrogallol 1,2-dioxygenase.

References

  • Groseclose EE, Ribbons DW (1981). "Metabolism of resorcinylic compounds by bacteria: new pathway for resorcinol catabolism in Azotobacter vinelandii". J. Bacteriol. 146 (2): 460–6. PMC  216987. PMID  7217008.