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Protoporphyrinogen IX dehydrogenase ( menaquinone)
Identifiers
EC no. 1.3.5.3
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum
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PMC articles
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NCBI proteins

Protoporphyrinogen IX dehydrogenase (menaquinone) ( EC 1.3.5.3, HemG) is an enzyme with systematic name protoporphyrinogen IX:menaquinone oxidoreductase. [1] This enzyme catalyses the following chemical reaction

protoporphyrinogen IX + 3 menaquinone protoporphyrin IX + 3 menaquinol

This enzyme enables Escherichia coli to synthesize heme in both aerobic and anaerobic environments.

References

  1. ^ Boynton TO, Daugherty LE, Dailey TA, Dailey HA (July 2009). "Identification of Escherichia coli HemG as a novel, menadione-dependent flavodoxin with protoporphyrinogen oxidase activity". Biochemistry. 48 (29): 6705–11. doi: 10.1021/bi900850y. PMC  2749469. PMID  19583219.

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