From Wikipedia, the free encyclopedia
Propatylnitrate
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Names
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IUPAC name
2,2-bis(nitrooxymethyl)butyl nitrate
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Identifiers
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ChEMBL
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ChemSpider
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ECHA InfoCard
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100.018.970
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UNII
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InChI=1S/C6H11N3O9/c1-2-6(3-16-7(10)11,4-17-8(12)13)5-18-9(14)15/h2-5H2,1H3 YKey: YZZCJYJBCUJISI-UHFFFAOYSA-N Y
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CCC(CO[N+](=O)[O-])(CO[N+](=O)[O-])CO[N+](=O)[O-]
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Properties
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C6H11N3O9
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Molar mass
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269.17 g/mol
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Pharmacology
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C01DA07 (
WHO)
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Except where otherwise noted, data are given for materials in their
standard state (at 25 °C [77 °F], 100 kPa).
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Chemical compound
Propatylnitrate (propatyl nitrate) is a
nitrovasodilator that is used as a medication against
angina pectoris.
[1]
References
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Forms | |
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Targets | |
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NO donors (
prodrugs) | |
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Enzyme (
inhibitors) | |
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Others |
- Indirect/downstream NO modulators:
ACE inhibitors/
AT-II receptor antagonists (e.g.,
captopril,
losartan)
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ETB receptor antagonists (e.g.,
bosentan)
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L-Type calcium channel
blockers (e.g.,
dihydropyridines:
nifedipine)
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Nebivolol (
beta blocker)
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PDE5 inhibitors (e.g.,
sildenafil)
- non-selective PDE inhibitors (e.g.,
caffeine)
- PDE9 inhibitors (e.g.,
paraxanthine)
- cGMP preferring PDE inhibitors (e.g., sildenafil, paraxanthine, tadalafil)
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Statins (e.g.,
simvastatin)
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