This enzyme belongs to the family of
oxidoreductases, specifically those acting on other nitrogenous compounds as donors with NAD+ or NADP+ as acceptor. The
systematic name of this enzyme class is 7-aminomethyl-7-carbaguanine:NADP+ oxidoreductase. Other names in common use include YkvM, QueF, preQ0 reductase, preQ0 oxidoreductase, 7-cyano-7-deazaguanine reductase, 7-aminomethyl-7-carbaguanine:NADP+ oxidoreductase, queuine synthase (incorrect as
queuine is not the product), and queuine:NADP+ oxidoreductase (incorrect as queuine is not the product).
Yokoyama S, Miyazawa T, Iitaka Y, Yamaizumi Z, Kasai H, Nishimura S (1979). "Three-dimensional structure of hyper-modified nucleoside Q located in the wobbling position of tRNA". Nature. 282 (5734): 107–9.
Bibcode:
1979Natur.282..107Y.
doi:
10.1038/282107a0.
PMID388227.
S2CID4313325.