Mugineic-acid 3-dioxygenase | |||||||||
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Identifiers | |||||||||
EC no. | 1.14.11.25 | ||||||||
Databases | |||||||||
IntEnz | IntEnz view | ||||||||
BRENDA | BRENDA entry | ||||||||
ExPASy | NiceZyme view | ||||||||
KEGG | KEGG entry | ||||||||
MetaCyc | metabolic pathway | ||||||||
PRIAM | profile | ||||||||
PDB structures | RCSB PDB PDBe PDBsum | ||||||||
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Mugineic-acid 3-dioxygenase ( EC 1.14.11.25, IDS2) is an enzyme with systematic name mugineic acid,2-oxoglutarate:oxygen oxidoreductase (3-hydroxylating). [1] [2] This enzyme catalyses the following chemical reaction
Mugineic-acid 3-dioxygenase contains iron(II). Mugineic acid is an amino acid excreted by some graminaceous (grassy) plants under conditions of iron deficiency as part of a strategy of solubilizing Fe from the root environment for uptake by the plant. Mugineic acid is closely related to its biochemical precursor, nicotianamine, and to a number of other compounds that also have been identified as phytosiderophores in graminaceous plants: 3-hydroxymugineic acid, 2'-deoxymugineic acid, avenic acid, and distichonic acid. The effectiveness of mugineic acid under iron-deficient conditions is dependent not only upon the iron chelating properties of the Fe-mugineic acid complex itself but also upon the presence of a plant membrane carrier that recognizes and absorbs the Fe-mugineic acid complex almost exclusively. [3]