Laryngo-onycho-cutaneous syndrome (also known as Shabbir syndrome) is a rare
epithelial disorder inherited in an
autosomal recessive fashion.[1][2] It is characterized by abnormalities in the
larynx,
nails ("
onycho-"), and skin ("cutaneous").[3] The disorder is only found in
Punjabi Muslims and only a few cases have been reported.[4]
^McLean, W. H. I. (2003-07-15). "An unusual N-terminal deletion of the laminin 3a isoform leads to the chronic granulation tissue disorder laryngo-onycho-cutaneous syndrome". Human Molecular Genetics. 12 (18): 2395–2409.
doi:
10.1093/hmg/ddg234.
ISSN1460-2083.
PMID12915477.