| guanosine phosphorylase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 2.4.2.15 | ||||||||
| CAS no. | 9030-28-8 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
In enzymology, a guanosine phosphorylase ( EC 2.4.2.15) is an enzyme that catalyzes the chemical reaction
- guanosine + phosphate guanine + alpha-D-ribose 1-phosphate
Thus, the two substrates of this enzyme are guanosine and phosphate, whereas its two products are guanine and alpha-D-ribose 1-phosphate.
This enzyme belongs to the family of glycosyltransferases, specifically the pentosyltransferases. The systematic name of this enzyme class is guanosine:phosphate alpha-D-ribosyltransferase. This enzyme participates in purine metabolism. [1]
References
- ^ Koszalka, G W; Vanhooke, J; Short, S A; Hall, W W (August 8, 1988). "Purification and properties of inosine-guanosine phosphorylase from Escherichia coli K-12". Journal of Bacteriology. 170 (8): 3493–3498. doi: 10.1128/jb.170.8.3493-3498.1988. ISSN 0021-9193. PMC 211319.
- Yamada EW (November 1961). "The phosphorolysis of nucleosides by rabbit bone marrow". The Journal of Biological Chemistry. 236: 3043–6. PMID 14008731.
