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cis-dihydroethylcatechol dehydrogenase
Identifiers
EC no. 1.3.1.66
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum
Gene Ontology AmiGO / QuickGO
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NCBI proteins

In enzymology, a cis-dihydroethylcatechol dehydrogenase ( EC 1.3.1.66) is an enzyme that catalyzes the chemical reaction

cis-1,2-dihydro-3-ethylcatechol + NAD+ 3-ethylcatechol + NADH + H+

Thus, the two substrates of this enzyme are cis-1,2-dihydro-3-ethylcatechol and NAD+, whereas its 3 products are 3-ethylcatechol, NADH, and H+.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-CH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is cis-1,2-dihydro-3-ethylcatechol:NAD+ oxidoreductase. This enzyme participates in ethylbenzene degradation.

References

  • Gibson DT, Gschwendt B, Yeh WK, Kobal VM (1973). "Initial reactions in the oxidation of ethylbenzene by Pseudomonas putida". Biochemistry. 12 (8): 1520–8. doi: 10.1021/bi00732a008. PMID  4699984.