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Catechol 2,3-dioxygenase
Catechol 2,3-dioxygenase tetramer, Pseudomonas alkylphenolica
Identifiers
EC no. 1.13.11.2
CAS no. 9029-46-3
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum
Search
PMC articles
PubMed articles
NCBI proteins

Catechol 2,3-dioxygenase ( EC 1.13.11.2, 2,3-pyrocatechase, catechol 2,3-oxygenase, catechol oxygenase, metapyrocatechase, pyrocatechol 2,3-dioxygenase) is an enzyme with systematic name catechol:oxygen 2,3-oxidoreductase (decyclizing). [1] [2] [3] [4] [5] This enzyme catalyses the following chemical reaction

catechol + O2 2-hydroxymuconate semialdehyde

This enzyme contains Fe(II).

References

  1. ^ Junker F, Field JA, Bangerter F, Ramsteiner K, Kohler HP, Joannou CL, Mason JR, Leisinger T, Cook AM (June 1994). "Oxygenation and spontaneous deamination of 2-aminobenzenesulphonic acid in Alcaligenes sp. strain O-1 with subsequent meta ring cleavage and spontaneous desulphonation to 2-hydroxymuconic acid". The Biochemical Journal. 300 ( Pt 2) (2): 429–36. doi: 10.1042/bj3000429. PMC  1138180. PMID  8002948.
  2. ^ Junker F, Leisinger T, Cook AM (July 1994). "3-Sulphocatechol 2,3-dioxygenase and other dioxygenases (EC 1.13.11.2 and EC 1.14.12.-) in the degradative pathways of 2-aminobenzenesulphonic, benzenesulphonic and 4-toluenesulphonic acids in Alcaligenes sp. strain O-1". Microbiology. 140 ( Pt 7) (7): 1713–22. doi: 10.1099/13500872-140-7-1713. PMID  8075807.
  3. ^ Hayaishi O, Lardy H, Myrbäck K (1963). "Direct oxygenation by O2, oxygenases". In Boyer PD (ed.). The Enzymes. Vol. 8 (2nd ed.). New York: Academic Press. pp. 353–371.
  4. ^ Kojima Y, Itada N, Hayaishi O (August 1961). "Metapyrocatachase: a new catechol-cleaving enzyme". The Journal of Biological Chemistry. 236: 2223–8. PMID  13757654.
  5. ^ Nozaki M, Kagamiyama H, Hayaishi O (1963). "Metapyrocatechase. I. Purification, Crystallization and Some Properties". Biochemische Zeitschrift. 338: 582–90. PMID  14087325.

External links