From Wikipedia, the free encyclopedia
Protein-coding gene in humans
Coatomer subunit gamma is a
protein that in humans is encoded by the COPG
gene .
[5]
[6] It is one of seven proteins in the
COPI coatomer complex that coats vesicles as they bud from the
Golgi complex.
[5]
Interactions
COPG has been shown to
interact with
Dopamine receptor D1 ,
[7]
COPZ1
[5]
[8] and
COPB1 .
[5]
[9]
References
^
a
b
c
GRCh38: Ensembl release 89: ENSG00000181789 –
Ensembl , May 2017
^
a
b
c
GRCm38: Ensembl release 89: ENSMUSG00000030058 –
Ensembl , May 2017
^
"Human PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .
^
"Mouse PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .
^
a
b
c
d Futatsumori M, Kasai K, Takatsu H, Shin HW, Nakayama K (February 2001). "Identification and characterization of novel isoforms of COP I subunits". J Biochem . 128 (5): 793–801.
doi :
10.1093/oxfordjournals.jbchem.a022817 .
PMID
11056392 .
^
"Entrez Gene: COPG coatomer protein complex, subunit gamma" .
^ Bermak, Jason C; Li Ming; Bullock Clayton; Weingarten Paul; Zhou Qun-Yong (February 2002). "Interaction of gamma-COP with a transport motif in the D1 receptor C-terminus". Eur. J. Cell Biol . 81 (2). Germany: 77–85.
doi :
10.1078/0171-9335-00222 .
ISSN
0171-9335 .
PMID
11893085 .
^ Faulstich, D; Auerbach S; Orci L; Ravazzola M; Wegchingel S; Lottspeich F; Stenbeck G; Harter C; Wieland F T; Tschochner H (October 1996).
"Architecture of coatomer: molecular characterization of delta-COP and protein interactions within the complex" (PDF) . J. Cell Biol . 135 (1). UNITED STATES: 53–61.
doi :
10.1083/jcb.135.1.53 .
ISSN
0021-9525 .
PMC
2121028 .
PMID
8858162 .
^ Lowe, M; Kreis T E (November 1996).
"In vivo assembly of coatomer, the COP-I coat precursor" . J. Biol. Chem . 271 (48). UNITED STATES: 30725–30.
doi :
10.1074/jbc.271.48.30725 .
ISSN
0021-9258 .
PMID
8940050 .
External links
Further reading
Lowe M, Kreis TE (1997).
"In vivo assembly of coatomer, the COP-I coat precursor" . J. Biol. Chem . 271 (48): 30725–30.
doi :
10.1074/jbc.271.48.30725 .
PMID
8940050 .
Pavel J, Harter C, Wieland FT (1998).
"Reversible dissociation of coatomer: functional characterization of a beta/delta-coat protein subcomplex" . Proc. Natl. Acad. Sci. U.S.A . 95 (5): 2140–5.
Bibcode :
1998PNAS...95.2140P .
doi :
10.1073/pnas.95.5.2140 .
PMC
19276 .
PMID
9482852 .
Fischer KD, Helms JB, Zhao L, Wieland FT (2000). "Site-specific photocrosslinking to probe interactions of Arf1 with proteins involved in budding of COPI vesicles". Methods . 20 (4): 455–64.
doi :
10.1006/meth.2000.0958 .
PMID
10720466 .
Eugster A, Frigerio G, Dale M, Duden R (2000).
"COP I domains required for coatomer integrity, and novel interactions with ARF and ARF-GAP" . EMBO J . 19 (15): 3905–17.
doi :
10.1093/emboj/19.15.3905 .
PMC
306616 .
PMID
10921873 .
Hu RM, Han ZG, Song HD, et al. (2000).
"Gene expression profiling in the human hypothalamus-pituitary-adrenal axis and full-length cDNA cloning" . Proc. Natl. Acad. Sci. U.S.A . 97 (17): 9543–8.
Bibcode :
2000PNAS...97.9543H .
doi :
10.1073/pnas.160270997 .
PMC
16901 .
PMID
10931946 .
Sullivan BM, Harrison-Lavoie KJ, Marshansky V, et al. (2000).
"RGS4 and RGS2 bind coatomer and inhibit COPI association with Golgi membranes and intracellular transport" . Mol. Biol. Cell . 11 (9): 3155–68.
doi :
10.1091/mbc.11.9.3155 .
PMC
14982 .
PMID
10982407 .
Hahn Y, Lee YJ, Yun JH, et al. (2000). "Duplication of genes encoding non-clathrin coat protein gamma-COP in vertebrate, insect and plant evolution". FEBS Lett . 482 (1–2): 31–6.
doi :
10.1016/S0014-5793(00)02033-0 .
PMID
11018518 .
S2CID
36356269 .
Paulsson KM, Kleijmeer MJ, Griffith J, et al. (2002).
"Association of tapasin and COPI provides a mechanism for the retrograde transport of major histocompatibility complex (MHC) class I molecules from the Golgi complex to the endoplasmic reticulum" . J. Biol. Chem . 277 (21): 18266–71.
doi :
10.1074/jbc.M201388200 .
PMID
11884415 .
Bermak JC, Li M, Bullock C, et al. (2002). "Interaction of gamma-COP with a transport motif in the D1 receptor C-terminus". Eur. J. Cell Biol . 81 (2): 77–85.
doi :
10.1078/0171-9335-00222 .
PMID
11893085 .
Kanzaki M, Watson RT, Hou JC, et al. (2003).
"Small GTP-binding protein TC10 differentially regulates two distinct populations of filamentous actin in 3T3L1 adipocytes" . Mol. Biol. Cell . 13 (7): 2334–46.
doi :
10.1091/mbc.01-10-0490 .
PMC
117317 .
PMID
12134073 .
Xu Y, Martin S, James DE, Hong W (2003).
"GS15 forms a SNARE complex with syntaxin 5, GS28, and Ykt6 and is implicated in traffic in the early cisternae of the Golgi apparatus" . Mol. Biol. Cell . 13 (10): 3493–507.
doi :
10.1091/mbc.E02-01-0004 .
PMC
129961 .
PMID
12388752 .
Strausberg RL, Feingold EA, Grouse LH, et al. (2003).
"Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences" . Proc. Natl. Acad. Sci. U.S.A . 99 (26): 16899–903.
Bibcode :
2002PNAS...9916899M .
doi :
10.1073/pnas.242603899 .
PMC
139241 .
PMID
12477932 .
Rohde HM, Cheong FY, Konrad G, et al. (2004).
"The human phosphatidylinositol phosphatase SAC1 interacts with the coatomer I complex" . J. Biol. Chem . 278 (52): 52689–99.
doi :
10.1074/jbc.M307983200 .
PMID
14527956 .
Watson PJ, Frigerio G, Collins BM, et al. (2004).
"Gamma-COP appendage domain - structure and function" . Traffic . 5 (2): 79–88.
doi :
10.1111/j.1600-0854.2004.00158.x .
PMID
14690497 .
S2CID
24249308 .
Ota T, Suzuki Y, Nishikawa T, et al. (2004).
"Complete sequencing and characterization of 21,243 full-length human cDNAs" . Nat. Genet . 36 (1): 40–5.
doi :
10.1038/ng1285 .
PMID
14702039 .
Gerhard DS, Wagner L, Feingold EA, et al. (2004).
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)" . Genome Res . 14 (10B): 2121–7.
doi :
10.1101/gr.2596504 .
PMC
528928 .
PMID
15489334 .
Ewing RM, Chu P, Elisma F, et al. (2007).
"Large-scale mapping of human protein-protein interactions by mass spectrometry" . Mol. Syst. Biol . 3 (1): 89.
doi :
10.1038/msb4100134 .
PMC
1847948 .
PMID
17353931 .