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Arsenate-mycothiol transferase
Identifiers
EC no. 2.8.4.2
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum
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PMC articles
PubMed articles
NCBI proteins

Arsenate-mycothiol transferase ( EC 2.8.4.2, ArsC1, ArsC2, mycothiol:arsenate transferase) is an enzyme with systematic name mycothiol:arsenate S-arsenotransferase. [1] This enzyme catalyses the following chemical reaction

mycothiol + arsenate arseno-mycothiol + H2O

Reduction of arsenate is part of a defence mechanism of the cell against toxic arsenate.

References

  1. ^ Ordóñez E, Van Belle K, Roos G, De Galan S, Letek M, Gil JA, Wyns L, Mateos LM, Messens J (May 2009). "Arsenate reductase, mycothiol, and mycoredoxin concert thiol/disulfide exchange". The Journal of Biological Chemistry. 284 (22): 15107–16. doi: 10.1074/jbc.m900877200. PMC  2685692. PMID  19286650.

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