| Acrylyl-CoA reductase (NADPH) | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 1.3.1.84 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
Acrylyl-CoA reductase (NADPH) ( EC 1.3.1.84) is an enzyme with systematic name propanoyl-CoA:NADP+ oxidoreductase. [1] [2] This enzyme catalyses the following chemical reaction
- propanoyl-CoA + NADP+ acryloyl-CoA + NADPH + H+
This enzyme catalyses a step in the 3-hydroxypropionate/4-hydroxybutyrate cycle, an autotrophic CO2 fixation pathway found in some Thermoacidophilic archaea.
References
- ^ Berg IA, Kockelkorn D, Buckel W, Fuchs G (December 2007). "A 3-hydroxypropionate/4-hydroxybutyrate autotrophic carbon dioxide assimilation pathway in Archaea". Science. 318 (5857): 1782–6. doi: 10.1126/science.1149976. PMID 18079405.
- ^ Teufel R, Kung JW, Kockelkorn D, Alber BE, Fuchs G (July 2009). "3-hydroxypropionyl-coenzyme A dehydratase and acryloyl-coenzyme A reductase, enzymes of the autotrophic 3-hydroxypropionate/4-hydroxybutyrate cycle in the Sulfolobales". Journal of Bacteriology. 191 (14): 4572–81. doi: 10.1128/JB.00068-09. PMC 2704735. PMID 19429610.
External links
- Acrylyl-CoA+reductase+(NADPH) at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
