(Redirected from
6-hydroxynicotinate 3-monooxygenase)
| 6-Hydroxynicotinate 3-monooxygenase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 1.14.13.114 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
6-Hydroxynicotinate 3-monooxygenase ( EC 1.14.13.114, NicC, 6HNA monooxygenase, HNA-3-monooxygenase) is an enzyme with systematic name 6-hydroxynicotinate,NADH:oxygen oxidoreductase (3-hydroxylating, decarboxylating). [1] [2] This enzyme catalyses the following chemical reaction
- 6-hydroxynicotinate + NADH + H+ + O2 2,5-dihydroxypyridine + NAD+ + H2O + CO2
6-Hydroxynicotinate 3-monooxygenase a flavoprotein (FAD).
References
- ^ Nakano H, Wieser M, Hurh B, Kawai T, Yoshida T, Yamane T, Nagasawa T (February 1999). "Purification, characterization and gene cloning of 6-hydroxynicotinate 3-monooxygenase from Pseudomonas fluorescens TN5". European Journal of Biochemistry. 260 (1): 120–6. doi: 10.1046/j.1432-1327.1999.00124.x. PMID 10091591.
- ^ Jiménez JI, Canales A, Jiménez-Barbero J, Ginalski K, Rychlewski L, García JL, Díaz E (August 2008). "Deciphering the genetic determinants for aerobic nicotinic acid degradation: the nic cluster from Pseudomonas putida KT2440". Proceedings of the National Academy of Sciences of the United States of America. 105 (32): 11329–34. Bibcode: 2008PNAS..10511329J. doi: 10.1073/pnas.0802273105. PMC 2516282. PMID 18678916.
External links
- 6-hydroxynicotinate+3-monooxygenase at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
