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(+)-Larreatricin hydroxylase
Identifiers
EC no. 1.14.99.47
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum
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PMC articles
PubMed articles
NCBI proteins

(+)-Larreatricin hydroxylase ( EC 1.14.99.47) is an enzyme with systematic name (+)-larreatricin:oxygen 3'-hydroxylase. [1] This enzyme catalyses the following chemical reaction

(+)-larreatricin + O2 + AH2 (+)-3'-hydroxylarreatricin + A + H2O

This enzyme is isolated from the plant Larrea tridentata (creosote bush) and can be produced recombinantly. [2]

References

  1. ^ Cho MH, Moinuddin SG, Helms GL, Hishiyama S, Eichinger D, Davin LB, Lewis NG (September 2003). "(+)-Larreatricin hydroxylase, an enantio-specific polyphenol oxidase from the creosote bush (Larrea tridentata)". Proceedings of the National Academy of Sciences of the United States of America. 100 (19): 10641–6. Bibcode: 2003PNAS..10010641C. doi: 10.1073/pnas.1934562100. PMC  196857. PMID  12960376.
  2. ^ Martin HJ, Kampatsikas I, Oost R, Pretzler M, Al-Sayed E, Roller A, et al. (October 2018). "Total Synthesis, Stereochemical Assignment, and Divergent Enantioselective Enzymatic Recognition of Larreatricin". Chemistry: A European Journal. 24 (59): 15756–15760. doi: 10.1002/chem.201803785. PMC  6220842. PMID  30113748.

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