(+)-Car-3-ene synthase (EC 4.2.3.107, 3-carene cyclase, 3-carene synthase, 3CAR, (+)-3-carene synthase) is an
enzyme with
systematic namegeranyl-diphosphate diphosphate-lyase [cyclizing, (+)-car-3-ene-forming].[1][2][3][4][5][6] This enzyme
catalyses the following
chemical reaction
The enzyme reacts with (3S)-linalyl diphosphate twice as rapidly as geranyl diphosphate.
References
^Savage TJ, Croteau R (September 1993). "Biosynthesis of monoterpenes: regio- and stereochemistry of (+)-3-carene biosynthesis". Archives of Biochemistry and Biophysics. 305 (2): 581–7.
doi:
10.1006/abbi.1993.1464.
PMID8373196.
^Savage TJ, Ichii H, Hume SD, Little DB, Croteau R (July 1995). "Monoterpene synthases from gymnosperms and angiosperms: stereospecificity and inactivation by cysteinyl- and arginyl-directed modifying reagents". Archives of Biochemistry and Biophysics. 320 (2): 257–65.
doi:
10.1016/0003-9861(95)90008-x.
PMID7625832.
^Hall DE, Robert JA, Keeling CI, Domanski D, Quesada AL, Jancsik S, Kuzyk MA, Hamberger B, Borchers CH, Bohlmann J (March 2011). "An integrated genomic, proteomic and biochemical analysis of (+)-3-carene biosynthesis in Sitka spruce (Picea sitchensis) genotypes that are resistant or susceptible to white pine weevil". The Plant Journal. 65 (6): 936–48.
doi:
10.1111/j.1365-313x.2010.04478.x.
PMID21323772.