October 22: Double Ninth Festival on Chinese lunar calendar ( 2004).
- 1383 - The 1383-1385 Crisis in Portugal: A period of civil war and anarchy began when King Fernando died without a male heir to the Portuguese throne.
- 1844 - Millerites and members of the Seventh-day Adventist Church were greatly disappointed that Jesus Christ did not return as predicted by preacher William Miller.
- 1962 - Cuban Missile Crisis: U.S. President John F. Kennedy announced on television that Soviet nuclear weapons had been discovered in Cuba, and that he had ordered a naval "quarantine" of the island nation.
Recent days: October 21 - October 20 - October 19